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    Akap11 A kinase (PRKA) anchor protein 11 [ Mus musculus (house mouse) ]

    Gene ID: 219181, updated on 31-Jan-2019

    Summary

    Official Symbol
    Akap11provided by MGI
    Official Full Name
    A kinase (PRKA) anchor protein 11provided by MGI
    Primary source
    MGI:MGI:2684060
    See related
    Ensembl:ENSMUSG00000022016
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm80; PRKA11; AKAP220; mKIAA0629; 6330501D17Rik
    Expression
    Broad expression in frontal lobe adult (RPKM 13.7), cortex adult (RPKM 12.2) and 25 other tissues See more
    Orthologs

    Genomic context

    See Akap11 in Genome Data Viewer
    Location:
    14; 14 D3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (78492246..78536985, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (78892053..78936667, complement)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 18277 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene diacylglycerol kinase, eta Neighboring gene predicted gene, 30716 Neighboring gene predicted gene, 18368

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    • G Protein Signaling Pathways, organism-specific biosystem (from WikiPathways)
      G Protein Signaling Pathways, organism-specific biosystemG proteins, short for guanine nucleotide-binding proteins, are a family of proteins involved in second messenger cascades. G proteins are so called because they function as "molecular switches". They...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    kinase regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein kinase A catalytic subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein kinase A regulatory subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    positive regulation of protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    peroxisome ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164503.1NP_001157975.1  A-kinase anchor protein 11 isoform 1

      See identical proteins and their annotated locations for NP_001157975.1

      Status: VALIDATED

      Source sequence(s)
      AC161608, AK032821, AK158300, AK164604
      Consensus CDS
      CCDS49549.1
      UniProtKB/TrEMBL
      E9Q774, Q8BSJ2
      Related
      ENSMUSP00000116015.2, ENSMUST00000123853.8
      Conserved Domains (1) summary
      cl14906
      Location:18081883
      AKAP_110; A-kinase anchor protein 110 kDa (AKAP 110)
    2. NM_001346784.1NP_001333713.1  A-kinase anchor protein 11 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC161608
      Consensus CDS
      CCDS84155.1
      UniProtKB/TrEMBL
      E9Q777

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      78492246..78536985 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006518901.3XP_006518964.2  A-kinase anchor protein 11 isoform X4

      Conserved Domains (1) summary
      cl14906
      Location:16381855
      AKAP_110; A-kinase anchor protein 110 kDa (AKAP 110)
    2. XM_006518899.3XP_006518962.2  A-kinase anchor protein 11 isoform X2

      See identical proteins and their annotated locations for XP_006518962.2

      UniProtKB/TrEMBL
      E9Q774
      Conserved Domains (1) summary
      cl14906
      Location:18081883
      AKAP_110; A-kinase anchor protein 110 kDa (AKAP 110)
    3. XM_006518898.3XP_006518961.2  A-kinase anchor protein 11 isoform X1

      See identical proteins and their annotated locations for XP_006518961.2

      UniProtKB/TrEMBL
      E9Q777
      Conserved Domains (1) summary
      cl14906
      Location:18091884
      AKAP_110; A-kinase anchor protein 110 kDa (AKAP 110)
    4. XM_017315981.1XP_017171470.1  A-kinase anchor protein 11 isoform X3

    5. XM_006518902.2XP_006518965.1  A-kinase anchor protein 11 isoform X1

      Related
      ENSMUSP00000022593.6, ENSMUST00000022593.6
      Conserved Domains (1) summary
      cl14906
      Location:18091884
      AKAP_110; A-kinase anchor protein 110 kDa (AKAP 110)
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