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    Mtmr6 myotubularin related protein 6 [ Mus musculus (house mouse) ]

    Gene ID: 219135, updated on 27-Jan-2018

    Summary

    Official Symbol
    Mtmr6provided by MGI
    Official Full Name
    myotubularin related protein 6provided by MGI
    Primary source
    MGI:MGI:2145637
    See related
    Ensembl:ENSMUSG00000021987
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI428804; AU041072; 4022440C11Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 32.5), cerebellum adult (RPKM 18.2) and 27 other tissues See more
    Orthologs

    Genomic context

    See Mtmr6 in Genome Data Viewer
    Location:
    14; 14 D1
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (60265178..60302371)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (60884065..60921207)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene nucleoporin like 1 Neighboring gene microRNA 719 Neighboring gene predicted gene, 38641 Neighboring gene predicted gene, 34874 Neighboring gene predicted gene, 34935 Neighboring gene APC membrane recruitment 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC27983

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    calcium-activated potassium channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylinositol phosphate phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylinositol-3,5-bisphosphate phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    phosphatidylinositol-3-phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    phosphatidylinositol dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    myotubularin-related protein 6
    Names
    mtmr6

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144843.4NP_659092.1  myotubularin-related protein 6

      See identical proteins and their annotated locations for NP_659092.1

      Status: VALIDATED

      Source sequence(s)
      AK076218, BE134918, BY274243, CB520796, CD563573
      Consensus CDS
      CCDS27176.1
      UniProtKB/Swiss-Prot
      Q8VE11
      Related
      ENSMUSP00000022563.7, ENSMUST00000022563.8
      Conserved Domains (2) summary
      cd13343
      Location:1101
      PH-GRAM_MTMR6; Myotubularian (MTM) related (MTMR) 6 protein Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam06602
      Location:107444
      Myotub-related; Myotubularin-like phosphatase domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      60265178..60302371
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017315972.1XP_017171461.1  myotubularin-related protein 6 isoform X2

    2. XM_017315971.1XP_017171460.1  myotubularin-related protein 6 isoform X1

      UniProtKB/TrEMBL
      L8AZD2
      Related
      ENSMUSP00000153403.1, ENSMUST00000224366.1
      Conserved Domains (2) summary
      cd13343
      Location:1101
      PH-GRAM_MTMR6; Myotubularian (MTM) related (MTMR) 6 protein Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
      pfam06602
      Location:107482
      Myotub-related; Myotubularin-like phosphatase domain
    3. XM_006518865.3XP_006518928.1  myotubularin-related protein 6 isoform X3

      Conserved Domains (2) summary
      pfam06602
      Location:101438
      Myotub-related; Myotubularin-like phosphatase domain
      cl17171
      Location:295
      PH-like; Pleckstrin homology-like domain
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