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    Dlgap5 DLG associated protein 5 [ Mus musculus (house mouse) ]

    Gene ID: 218977, updated on 16-Oct-2021

    Summary

    Official Symbol
    Dlgap5provided by MGI
    Official Full Name
    DLG associated protein 5provided by MGI
    Primary source
    MGI:MGI:2183453
    See related
    Ensembl:ENSMUSG00000037544
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Dlg7; Hurp; Dap-5; C77459; C86398; mKIAA0008
    Expression
    Biased expression in liver E14 (RPKM 20.5), liver E14.5 (RPKM 17.2) and 10 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Dlgap5 in Genome Data Viewer
    Location:
    14 C1; 14 24.6 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (47625236..47655864, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (47387779..47418407, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (48007454..48038082, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52166 Neighboring gene lectin, galactose binding, soluble 3 Neighboring gene ribosomal protein S15 pseudogene Neighboring gene F-box protein 34 Neighboring gene predicted gene, 35166

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in centrosome localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in chromosome segregation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in kinetochore assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitotic spindle organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in signaling IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in spindle pole centrosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in spindle pole centrosome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    disks large-associated protein 5
    Names
    discs, large homolog 7
    discs, large homolog-associated protein 5
    hepatoma up-regulated protein homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144553.2NP_653136.2  disks large-associated protein 5

      See identical proteins and their annotated locations for NP_653136.2

      Status: VALIDATED

      Source sequence(s)
      AB076696, AC123665, AK085882
      Consensus CDS
      CCDS26987.1
      UniProtKB/Swiss-Prot
      Q8K4R9
      UniProtKB/TrEMBL
      A0A0R4J0G7
      Related
      ENSMUSP00000040416.4, ENSMUST00000043296.10
      Conserved Domains (1) summary
      pfam03359
      Location:397543
      GKAP; Guanylate-kinase-associated protein (GKAP) protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      47625236..47655864 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006518835.5XP_006518898.1  disks large-associated protein 5 isoform X3

      Conserved Domains (1) summary
      pfam03359
      Location:399543
      GKAP; Guanylate-kinase-associated protein (GKAP) protein
    2. XM_006518833.2XP_006518896.1  disks large-associated protein 5 isoform X1

      Conserved Domains (1) summary
      pfam03359
      Location:387531
      GKAP; Guanylate-kinase-associated protein (GKAP) protein
    3. XM_006518834.2XP_006518897.1  disks large-associated protein 5 isoform X2

      Related
      ENSMUSP00000153953.2, ENSMUST00000180299.8
      Conserved Domains (1) summary
      pfam03359
      Location:399543
      GKAP; Guanylate-kinase-associated protein (GKAP) protein

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001145949.1: Suppressed sequence

      Description
      NM_001145949.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein, and the transcript appears incompletely processed at its 3' end.
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