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    Ccno cyclin O [ Mus musculus (house mouse) ]

    Gene ID: 218630, updated on 31-Jan-2019

    Summary

    Official Symbol
    Ccnoprovided by MGI
    Official Full Name
    cyclin Oprovided by MGI
    Primary source
    MGI:MGI:2145534
    See related
    Ensembl:ENSMUSG00000042417
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ccnu; UDG2; Ung2; C86987; E130318K11
    Expression
    Biased expression in genital fat pad adult (RPKM 26.2), ovary adult (RPKM 22.7) and 2 other tissues See more
    Orthologs

    Genomic context

    See Ccno in Genome Data Viewer
    Location:
    13; 13 D2.2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (112987802..112990778)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (113778010..113780986)

    Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene phospholipid phosphatase 1 Neighboring gene Mtr4 exosome RNA helicase Neighboring gene 40S ribosomal protein S13-like Neighboring gene DEAH (Asp-Glu-Ala-His) box polypeptide 29 Neighboring gene multiciliate differentiation and DNA synthesis associated cell cycle protein Neighboring gene microRNA 449c Neighboring gene cell division cycle 20B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cyclin-dependent protein serine/threonine kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    cell projection organization IEA
    Inferred from Electronic Annotation
    more info
     
    cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    multi-ciliated epithelial cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    positive regulation of cell proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of cyclin-dependent protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of mitotic nuclear division IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cyclin-dependent protein kinase holoenzyme complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    cyclin-O
    Names
    cyclin U
    cyclin-like uracil-DNA glycosylase
    uracil DNA glycosylase 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081062.1NP_001074531.1  cyclin-O

      See identical proteins and their annotated locations for NP_001074531.1

      Status: VALIDATED

      Source sequence(s)
      AC165265
      Consensus CDS
      CCDS36782.1
      UniProtKB/Swiss-Prot
      P0C242
      UniProtKB/TrEMBL
      B2RWG0
      Related
      ENSMUSP00000040083.4, ENSMUST00000038404.5
      Conserved Domains (2) summary
      pfam00134
      Location:108231
      Cyclin_N; Cyclin, N-terminal domain
      pfam02984
      Location:233301
      Cyclin_C; Cyclin, C-terminal domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

      Range
      112987802..112990778
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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