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    Nup153 nucleoporin 153 [ Mus musculus (house mouse) ]

    Gene ID: 218210, updated on 23-Jun-2021

    Summary

    Official Symbol
    Nup153provided by MGI
    Official Full Name
    nucleoporin 153provided by MGI
    Primary source
    MGI:MGI:2385621
    See related
    Ensembl:ENSMUSG00000021374
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C88147; B130015D15Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 42.1), thymus adult (RPKM 15.1) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Nup153 in Genome Data Viewer
    Location:
    13; 13 A5
    Exon count:
    24
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (46833369..46890682, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (46679902..46727849, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (46775271..46823218, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene CAP, adenylate cyclase-associated protein, 2 (yeast) Neighboring gene VISTA enhancer mm132 Neighboring gene family with sequence similarity 8, member A1 Neighboring gene predicted gene, 46412 Neighboring gene kinesin family member 13A Neighboring gene predicted gene, 24620 Neighboring gene predicted gene, 22960

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nuclear localization sequence binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nuclear localization sequence binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-membrane adaptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables structural constituent of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables structural constituent of nuclear pore ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in RNA export from nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitotic cell cycle ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of RNA export from nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in nuclear pore complex assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein import into nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in annulate lamellae ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear inclusion body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear periphery ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nuclear pore IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of nuclear pore ISO
    Inferred from Sequence Orthology
    more info
     
    part_of nuclear pore nuclear basket ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasmic side of nuclear pore ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    nuclear pore complex protein Nup153

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175749.2NP_786925.2  nuclear pore complex protein Nup153

      Status: VALIDATED

      Source sequence(s)
      AK031006, AK044947, AK086847, BM950067, CA326562, CF897724, CF898039, CK638380
      Consensus CDS
      CCDS26486.1
      UniProtKB/TrEMBL
      E9Q3G8, Q3V3W1, Q8BRF6
      Related
      ENSMUSP00000021803.9, ENSMUST00000021803.10
      Conserved Domains (4) summary
      sd00025
      Location:658677
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam00641
      Location:718746
      zf-RanBP; Zn-finger in Ran binding protein and others
      pfam08604
      Location:114625
      Nup153; Nucleoporin Nup153-like
      pfam10599
      Location:13721462
      Nup_retrotrp_bd; Retro-transposon transporting motif

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      46833369..46890682 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157992.1XP_036013885.1  nuclear pore complex protein Nup153 isoform X1

      Conserved Domains (4) summary
      sd00025
      Location:367386
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam10599
      Location:10811171
      Nup_retrotrp_bd; Retro-transposon transporting motif
      pfam00641
      Location:427455
      zf-RanBP; Zn-finger in Ran binding protein and others
      pfam08604
      Location:1326
      Nup153; Nucleoporin Nup153-like
    2. XM_036157993.1XP_036013886.1  nuclear pore complex protein Nup153 isoform X2

      Conserved Domains (4) summary
      sd00025
      Location:147166
      zf-RanBP2; RanBP2-type Zn finger [structural motif]
      pfam10599
      Location:861951
      Nup_retrotrp_bd; Retro-transposon transporting motif
      pfam00641
      Location:207235
      zf-RanBP; Zn-finger in Ran binding protein and others
      pfam08604
      Location:1106
      Nup153; Nucleoporin Nup153-like
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