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    Pacs2 phosphofurin acidic cluster sorting protein 2 [ Mus musculus (house mouse) ]

    Gene ID: 217893, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pacs2provided by MGI
    Official Full Name
    phosphofurin acidic cluster sorting protein 2provided by MGI
    Primary source
    MGI:MGI:1924399
    See related
    Ensembl:ENSMUSG00000021143
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Pa; Pacs1l; AW208651; AW489976; mKIAA0602; E230011J22; 6720425G15Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 55.1), cerebellum adult (RPKM 32.8) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Pacs2 in Genome Data Viewer
    Location:
    12; 12 F1
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (112977998..113038021)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (113014454..113074401)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (114252719..114312612)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit Neighboring gene BTB (POZ) domain containing 6 Neighboring gene RIKEN cDNA 9230104M06 gene Neighboring gene testis expressed gene 22 Neighboring gene metastasis associated 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables transmembrane transporter binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    phosphofurin acidic cluster sorting protein 2
    Names
    PACS1-like protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081170.1NP_001074639.1  phosphofurin acidic cluster sorting protein 2 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the coding region compared to variant 1. The resulting protein (isoform 2) is shorter but has the same N- and C-termini compared to isoform 1.
      Source sequence(s)
      AC073562
      Consensus CDS
      CCDS36573.1
      UniProtKB/TrEMBL
      E9Q7E9
      Related
      ENSMUSP00000081953.5, ENSMUST00000084891.5
      Conserved Domains (1) summary
      pfam10254
      Location:474888
      Pacs-1; PACS-1 cytosolic sorting protein
    2. NM_001291444.1NP_001278373.1  phosphofurin acidic cluster sorting protein 2 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1).
      Source sequence(s)
      AC073562
      Consensus CDS
      CCDS88411.1
      UniProtKB/TrEMBL
      A0A1Y7VLZ7
      Related
      ENSMUSP00000152439.2, ENSMUST00000223502.2
      Conserved Domains (1) summary
      pfam10254
      Location:476890
      Pacs-1; PACS-1 cytosolic sorting protein
    3. NM_001291445.1NP_001278374.1  phosphofurin acidic cluster sorting protein 2 isoform 3

      See identical proteins and their annotated locations for NP_001278374.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate exon and uses an alternate splice site in the coding region compared to variant 1. The resulting protein (isoform 3) is shorter but has the same N- and C-termini compared to isoform 1.
      Source sequence(s)
      AC073562
      Consensus CDS
      CCDS88412.1
      UniProtKB/Swiss-Prot
      Q3V3Q7
      Related
      ENSMUSP00000152145.2, ENSMUST00000220541.2
      Conserved Domains (1) summary
      pfam10254
      Location:444858
      Pacs-1; PACS-1 cytosolic sorting protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      112977998..113038021
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157368.1XP_036013261.1  phosphofurin acidic cluster sorting protein 2 isoform X3

      Conserved Domains (1) summary
      pfam10254
      Location:476866
      Pacs-1; PACS-1 cytosolic sorting protein
    2. XM_006515769.4XP_006515832.1  phosphofurin acidic cluster sorting protein 2 isoform X1

      Conserved Domains (1) summary
      pfam10254
      Location:476912
      Pacs-1; PACS-1 cytosolic sorting protein
    3. XM_006515773.4XP_006515836.1  phosphofurin acidic cluster sorting protein 2 isoform X7

      Conserved Domains (1) summary
      pfam10254
      Location:476901
      Pacs-1; PACS-1 cytosolic sorting protein
    4. XM_006515772.4XP_006515835.1  phosphofurin acidic cluster sorting protein 2 isoform X6

      Conserved Domains (1) summary
      pfam10254
      Location:476901
      Pacs-1; PACS-1 cytosolic sorting protein
    5. XM_006515770.4XP_006515833.1  phosphofurin acidic cluster sorting protein 2 isoform X2

      Conserved Domains (1) summary
      pfam10254
      Location:474910
      Pacs-1; PACS-1 cytosolic sorting protein
    6. XM_030246678.2XP_030102538.1  phosphofurin acidic cluster sorting protein 2 isoform X9

      Conserved Domains (1) summary
      pfam10254
      Location:474899
      Pacs-1; PACS-1 cytosolic sorting protein
    7. XM_006515774.4XP_006515837.1  phosphofurin acidic cluster sorting protein 2 isoform X8

      Conserved Domains (1) summary
      pfam10254
      Location:474899
      Pacs-1; PACS-1 cytosolic sorting protein
    8. XM_006515771.3XP_006515834.1  phosphofurin acidic cluster sorting protein 2 isoform X4

      Conserved Domains (1) summary
      pfam10254
      Location:468904
      Pacs-1; PACS-1 cytosolic sorting protein
    9. XM_030246677.2XP_030102537.1  phosphofurin acidic cluster sorting protein 2 isoform X5

      Conserved Domains (1) summary
      pfam10254
      Location:466902
      Pacs-1; PACS-1 cytosolic sorting protein
    10. XM_030246679.2XP_030102539.1  phosphofurin acidic cluster sorting protein 2 isoform X10

      Conserved Domains (1) summary
      pfam10254
      Location:466891
      Pacs-1; PACS-1 cytosolic sorting protein
    11. XM_006515777.3XP_006515840.1  phosphofurin acidic cluster sorting protein 2 isoform X11

      Conserved Domains (1) summary
      pfam10254
      Location:466880
      Pacs-1; PACS-1 cytosolic sorting protein
    12. XM_006515779.4XP_006515842.1  phosphofurin acidic cluster sorting protein 2 isoform X15

      Conserved Domains (1) summary
      pfam10254
      Location:476507
      Pacs-1; PACS-1 cytosolic sorting protein
    13. XM_006515778.2XP_006515841.1  phosphofurin acidic cluster sorting protein 2 isoform X12

      Conserved Domains (1) summary
      pfam10254
      Location:409845
      Pacs-1; PACS-1 cytosolic sorting protein
    14. XM_036157370.1XP_036013263.1  phosphofurin acidic cluster sorting protein 2 isoform X14

      Conserved Domains (1) summary
      pfam10254
      Location:407821
      Pacs-1; PACS-1 cytosolic sorting protein
    15. XM_030246681.2XP_030102541.1  phosphofurin acidic cluster sorting protein 2 isoform X12

      Conserved Domains (1) summary
      pfam10254
      Location:409845
      Pacs-1; PACS-1 cytosolic sorting protein
    16. XM_030246680.2XP_030102540.1  phosphofurin acidic cluster sorting protein 2 isoform X13

      Conserved Domains (1) summary
      pfam10254
      Location:407843
      Pacs-1; PACS-1 cytosolic sorting protein

    RNA

    1. XR_381518.4 RNA Sequence

    2. XR_381519.5 RNA Sequence

    3. XR_004937491.1 RNA Sequence

    4. XR_003950043.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_198165.1: Suppressed sequence

      Description
      NM_198165.1: This RefSeq was removed because currently there is insufficient support for the transcript and protein.
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