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    Sipa1l1 signal-induced proliferation-associated 1 like 1 [ Mus musculus (house mouse) ]

    Gene ID: 217692, updated on 9-Dec-2024

    Summary

    Official Symbol
    Sipa1l1provided by MGI
    Official Full Name
    signal-induced proliferation-associated 1 like 1provided by MGI
    Primary source
    MGI:MGI:2443679
    See related
    Ensembl:ENSMUSG00000042700 AllianceGenome:MGI:2443679
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Spar; mKIAA0440; 4931426N11Rik
    Summary
    Enables ephrin receptor binding activity. Involved in ephrin receptor signaling pathway and regulation of axonogenesis. Predicted to be located in several cellular components, including dendritic spine; neuronal cell body; and postsynaptic density. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm; glutamatergic synapse; and postsynapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and integumental system. Orthologous to human SIPA1L1 (signal induced proliferation associated 1 like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 37.5), cortex adult (RPKM 30.3) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Sipa1l1 in Genome Data Viewer
    Location:
    12 D1; 12 38.14 cM
    Exon count:
    30
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (82216138..82498560)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (82169377..82451786)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene pecanex 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:83072406-83072559 Neighboring gene STARR-seq mESC enhancer starr_32682 Neighboring gene predicted gene, 30799 Neighboring gene STARR-seq mESC enhancer starr_32683 Neighboring gene STARR-positive B cell enhancer ABC_E7158 Neighboring gene STARR-positive B cell enhancer ABC_E4035 Neighboring gene STARR-positive B cell enhancer ABC_E11517 Neighboring gene predicted gene, 30916 Neighboring gene STARR-seq mESC enhancer starr_32692 Neighboring gene STARR-seq mESC enhancer starr_32693 Neighboring gene predicted gene, 51987 Neighboring gene predicted gene, 31064 Neighboring gene predicted gene, 30966 Neighboring gene general transcription factor II A, 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Gene trapped (1) 
    • Targeted (3)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables actin filament binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ephrin receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin protein ligase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in actin cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in actin cytoskeleton organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in activation of GTPase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in ephrin receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in postsynaptic actin cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of GTPase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of axonogenesis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of dendrite morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of dendritic spine morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of dendritic spine morphogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of postsynaptic density assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of small GTPase mediated signal transduction IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of synaptic plasticity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of synaptic plasticity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in actin cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in dendritic spine ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendritic spine ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in postsynapse ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    located_in postsynaptic density ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    signal-induced proliferation-associated 1-like protein 1
    Names
    SIPA1-like protein 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001167983.1NP_001161455.1  signal-induced proliferation-associated 1-like protein 1 isoform 2

      See identical proteins and their annotated locations for NP_001161455.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate donor splice site at the penultimate coding exon compared to variant 1, resulting in a frame-shift, and a shorter isoform (2) with a distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AK078420, AK122284, BC058681, BP765364
      Consensus CDS
      CCDS49105.1
      UniProtKB/Swiss-Prot
      Q8C0T5
      Related
      ENSMUSP00000152356.2, ENSMUST00000222298.2
      Conserved Domains (3) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam11881
      Location:14831727
      SPAR_C; C-terminal domain of SPAR protein
    2. NM_001407402.1NP_001394331.1  signal-induced proliferation-associated 1-like protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
    3. NM_001407403.1NP_001394332.1  signal-induced proliferation-associated 1-like protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
      UniProtKB/Swiss-Prot
      Q6PDI8, Q80U02, Q8C026, Q8C0T5
      Related
      ENSMUSP00000131030.3, ENSMUST00000166429.9
    4. NM_001407404.1NP_001394333.1  signal-induced proliferation-associated 1-like protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
      UniProtKB/Swiss-Prot
      Q6PDI8, Q80U02, Q8C026, Q8C0T5
    5. NM_001407405.1NP_001394334.1  signal-induced proliferation-associated 1-like protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
      UniProtKB/Swiss-Prot
      Q6PDI8, Q80U02, Q8C026, Q8C0T5
    6. NM_001407406.1NP_001394335.1  signal-induced proliferation-associated 1-like protein 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC156643
      UniProtKB/Swiss-Prot
      Q6PDI8, Q80U02, Q8C026, Q8C0T5
      Related
      ENSMUSP00000061014.7, ENSMUST00000053969.7
    7. NM_001407407.1NP_001394336.1  signal-induced proliferation-associated 1-like protein 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC156643
    8. NM_001407408.1NP_001394337.1  signal-induced proliferation-associated 1-like protein 1 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
    9. NM_001407409.1NP_001394338.1  signal-induced proliferation-associated 1-like protein 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
    10. NM_001407410.1NP_001394339.1  signal-induced proliferation-associated 1-like protein 1 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
    11. NM_001407411.1NP_001394340.1  signal-induced proliferation-associated 1-like protein 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
      UniProtKB/TrEMBL
      Q4VBF8
      Related
      ENSMUSP00000152681.2, ENSMUST00000220963.2
    12. NM_001407412.1NP_001394341.1  signal-induced proliferation-associated 1-like protein 1 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
      UniProtKB/TrEMBL
      Q4VBF8
    13. NM_001407413.1NP_001394342.1  signal-induced proliferation-associated 1-like protein 1 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
    14. NM_001407414.1NP_001394343.1  signal-induced proliferation-associated 1-like protein 1 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
    15. NM_001407415.1NP_001394344.1  signal-induced proliferation-associated 1-like protein 1 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
    16. NM_172579.4NP_766167.2  signal-induced proliferation-associated 1-like protein 1 isoform 1

      See identical proteins and their annotated locations for NP_766167.2

      Status: VALIDATED

      Source sequence(s)
      AC122227, AC130222, AC156643
      Consensus CDS
      CCDS26026.1
      UniProtKB/Swiss-Prot
      Q6PDI8, Q80U02, Q8C026, Q8C0T5
      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17151770
      ZapB; Cell division protein ZapB
      pfam11881
      Location:14831727
      SPAR_C; C-terminal domain of SPAR protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      82216138..82498560
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011244060.4XP_011242362.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011242362.1

      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17291784
      ZapB; Cell division protein ZapB
      pfam11881
      Location:14961741
      SPAR_C; C-terminal domain of SPAR protein
    2. XM_011244067.4XP_011242369.1  signal-induced proliferation-associated 1-like protein 1 isoform X2

      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17281783
      ZapB; Cell division protein ZapB
      pfam11881
      Location:15001740
      SPAR_C; C-terminal domain of SPAR protein
    3. XM_011244061.3XP_011242363.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011242363.1

      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17291784
      ZapB; Cell division protein ZapB
      pfam11881
      Location:14961741
      SPAR_C; C-terminal domain of SPAR protein
    4. XM_036157315.1XP_036013208.1  signal-induced proliferation-associated 1-like protein 1 isoform X3

      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17161771
      ZapB; Cell division protein ZapB
      pfam11881
      Location:14831728
      SPAR_C; C-terminal domain of SPAR protein
    5. XM_017315025.2XP_017170514.1  signal-induced proliferation-associated 1-like protein 1 isoform X4

      UniProtKB/Swiss-Prot
      Q6PDI8, Q80U02, Q8C026, Q8C0T5
      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17151770
      ZapB; Cell division protein ZapB
      pfam11881
      Location:14831727
      SPAR_C; C-terminal domain of SPAR protein
    6. XM_017315027.2XP_017170516.1  signal-induced proliferation-associated 1-like protein 1 isoform X5

      Conserved Domains (4) summary
      cd00992
      Location:459529
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:135315
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:12351290
      ZapB; Cell division protein ZapB
      pfam11881
      Location:10061247
      SPAR_C; C-terminal domain of SPAR protein
    7. XM_017315026.2XP_017170515.1  signal-induced proliferation-associated 1-like protein 1 isoform X5

      Conserved Domains (4) summary
      cd00992
      Location:459529
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:135315
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:12351290
      ZapB; Cell division protein ZapB
      pfam11881
      Location:10061247
      SPAR_C; C-terminal domain of SPAR protein
    8. XM_030246655.1XP_030102515.1  signal-induced proliferation-associated 1-like protein 1 isoform X5

      Conserved Domains (4) summary
      cd00992
      Location:459529
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:135315
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:12351290
      ZapB; Cell division protein ZapB
      pfam11881
      Location:10061247
      SPAR_C; C-terminal domain of SPAR protein
    9. XM_030246653.2XP_030102513.1  signal-induced proliferation-associated 1-like protein 1 isoform X5

      Conserved Domains (4) summary
      cd00992
      Location:459529
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:135315
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:12351290
      ZapB; Cell division protein ZapB
      pfam11881
      Location:10061247
      SPAR_C; C-terminal domain of SPAR protein
    10. XM_030246652.1XP_030102512.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17291784
      ZapB; Cell division protein ZapB
      pfam11881
      Location:14961741
      SPAR_C; C-terminal domain of SPAR protein
    11. XM_030246656.1XP_030102516.1  signal-induced proliferation-associated 1-like protein 1 isoform X5

      Conserved Domains (4) summary
      cd00992
      Location:459529
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:135315
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:12351290
      ZapB; Cell division protein ZapB
      pfam11881
      Location:10061247
      SPAR_C; C-terminal domain of SPAR protein
    12. XM_011244064.4XP_011242366.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011242366.1

      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17291784
      ZapB; Cell division protein ZapB
      pfam11881
      Location:14961741
      SPAR_C; C-terminal domain of SPAR protein
    13. XM_011244066.4XP_011242368.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011242368.1

      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17291784
      ZapB; Cell division protein ZapB
      pfam11881
      Location:14961741
      SPAR_C; C-terminal domain of SPAR protein
    14. XM_011244063.4XP_011242365.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011242365.1

      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17291784
      ZapB; Cell division protein ZapB
      pfam11881
      Location:14961741
      SPAR_C; C-terminal domain of SPAR protein
    15. XM_030246654.2XP_030102514.1  signal-induced proliferation-associated 1-like protein 1 isoform X5

      Conserved Domains (4) summary
      cd00992
      Location:459529
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:135315
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:12351290
      ZapB; Cell division protein ZapB
      pfam11881
      Location:10061247
      SPAR_C; C-terminal domain of SPAR protein
    16. XM_030246657.2XP_030102517.1  signal-induced proliferation-associated 1-like protein 1 isoform X5

      Conserved Domains (4) summary
      cd00992
      Location:459529
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:135315
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:12351290
      ZapB; Cell division protein ZapB
      pfam11881
      Location:10061247
      SPAR_C; C-terminal domain of SPAR protein
    17. XM_036157314.1XP_036013207.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17291784
      ZapB; Cell division protein ZapB
      pfam11881
      Location:14961741
      SPAR_C; C-terminal domain of SPAR protein
    18. XM_011244062.2XP_011242364.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_011242364.1

      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17291784
      ZapB; Cell division protein ZapB
      pfam11881
      Location:14961741
      SPAR_C; C-terminal domain of SPAR protein
    19. XM_006515684.3XP_006515747.1  signal-induced proliferation-associated 1-like protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006515747.1

      Conserved Domains (4) summary
      cd00992
      Location:9531023
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:629809
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:17291784
      ZapB; Cell division protein ZapB
      pfam11881
      Location:14961741
      SPAR_C; C-terminal domain of SPAR protein
    20. XM_017315029.1XP_017170518.1  signal-induced proliferation-associated 1-like protein 1 isoform X6

      Conserved Domains (4) summary
      cd00992
      Location:428498
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam02145
      Location:104284
      Rap_GAP; Rap/ran-GAP
      pfam06005
      Location:12041259
      ZapB; Cell division protein ZapB
      pfam11881
      Location:9751216
      SPAR_C; C-terminal domain of SPAR protein