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    Utp18 UTP18 small subunit processome component [ Mus musculus (house mouse) ]

    Gene ID: 217109, updated on 5-Aug-2018

    Summary

    Official Symbol
    Utp18provided by MGI
    Official Full Name
    UTP18 small subunit processome componentprovided by MGI
    Primary source
    MGI:MGI:1923402
    See related
    Ensembl:ENSMUSG00000054079 Vega:OTTMUSG00000001465
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Wdr50; 6430513M13; 6230425C22Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 9.2), placenta adult (RPKM 6.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Utp18 in Genome Data Viewer
    Location:
    11; 11 D
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (93859243..93885831, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (93720557..93747080, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene predicted gene 11502 Neighboring gene predicted gene, 35148 Neighboring gene mbt domain containing 1 Neighboring gene NME/NM23 nucleoside diphosphate kinase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC141453, MGC141454

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    rRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Pwp2p-containing subcomplex of 90S preribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear membrane ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    small-subunit processome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    U3 small nucleolar RNA-associated protein 18 homolog
    Names
    UTP18, small subunit (SSU) processome component, homolog
    WD repeat domain 50
    WD repeat-containing protein 50

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013375.1NP_001013393.1  U3 small nucleolar RNA-associated protein 18 homolog

      See identical proteins and their annotated locations for NP_001013393.1

      Status: VALIDATED

      Source sequence(s)
      AK032265, AK078033, BC119622, BG067111, BY743008
      Consensus CDS
      CCDS25245.1
      UniProtKB/Swiss-Prot
      Q5SSI6
      UniProtKB/TrEMBL
      Q3U3Q3, Q8BHW1
      Related
      ENSMUSP00000068103.3, OTTMUSP00000001410, ENSMUST00000066888.9, OTTMUST00000002887
      Conserved Domains (3) summary
      COG2319
      Location:217547
      WD40; WD40 repeat [General function prediction only]
      sd00039
      Location:250290
      7WD40; WD40 repeat [structural motif]
      cl02567
      Location:250488
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      93859243..93885831 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017314477.1XP_017169966.1  U3 small nucleolar RNA-associated protein 18 homolog isoform X1

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