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    Rufy1 RUN and FYVE domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 216724, updated on 12-Aug-2018

    Summary

    Official Symbol
    Rufy1provided by MGI
    Official Full Name
    RUN and FYVE domain containing 1provided by MGI
    Primary source
    MGI:MGI:2429762
    See related
    Ensembl:ENSMUSG00000020375 Vega:OTTMUSG00000005584
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rabip4; ZFYVE12; 3000002E04Rik
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 5.9), adrenal adult (RPKM 5.7) and 28 other tissues See more
    Orthologs

    Genomic context

    See Rufy1 in Genome Data Viewer
    Location:
    11; 11 B1.3
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (50389286..50431605, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (50202805..50244613, complement)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene microRNA 804 Neighboring gene heterogeneous nuclear ribonucleoprotein H1 Neighboring gene predicted gene, 36763 Neighboring gene predicted gene, 46259

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    SH2 domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    SH3 domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein transporter activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    endocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of endocytosis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of endocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    NOT cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endosome ISO
    Inferred from Sequence Orthology
    more info
     
    intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    NOT late endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear speck ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    RUN and FYVE domain-containing protein 1
    Names
    FYVE-finger containing protein
    Rab4a interacting protein
    rab4-interacting protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172557.3NP_766145.1  RUN and FYVE domain-containing protein 1

      See identical proteins and their annotated locations for NP_766145.1

      Status: VALIDATED

      Source sequence(s)
      AK046625, AK046633, BQ176179
      Consensus CDS
      CCDS24635.1
      UniProtKB/Swiss-Prot
      Q8BIJ7
      Related
      ENSMUSP00000020643.3, OTTMUSP00000005747, ENSMUST00000020643.3
      Conserved Domains (3) summary
      cd15758
      Location:638708
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:151274
      RUN; RUN domain
      cl02073
      Location:444589
      DUF3422; Protein of unknown function (DUF3422)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      50389286..50431605 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532841.3XP_006532904.1  RUN and FYVE domain-containing protein 1 isoform X1

      Conserved Domains (3) summary
      cd15758
      Location:545615
      FYVE_RUFY1; FYVE domain found in RUN and FYVE domain-containing protein 1 (RUFY1) and similar proteins
      pfam02759
      Location:58181
      RUN; RUN domain
      cl02073
      Location:351496
      DUF3422; Protein of unknown function (DUF3422)
    2. XM_017314443.1XP_017169932.1  RUN and FYVE domain-containing protein 1 isoform X3

    3. XM_017314442.1XP_017169931.1  RUN and FYVE domain-containing protein 1 isoform X2

    RNA

    1. XR_001779949.1 RNA Sequence

    2. XR_001779948.1 RNA Sequence

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