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    Clint1 clathrin interactor 1 [ Mus musculus (house mouse) ]

    Gene ID: 216705, updated on 31-Jan-2019

    Summary

    Official Symbol
    Clint1provided by MGI
    Official Full Name
    clathrin interactor 1provided by MGI
    Primary source
    MGI:MGI:2144243
    See related
    Ensembl:ENSMUSG00000006169
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Enth; Epn4; AI642036; AW537616; C530049I24Rik; F630206G17Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 47.1), genital fat pad adult (RPKM 44.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Clint1 in Genome Data Viewer
    Location:
    11; 11 B1.1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (45851932..45910625)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (45665466..45724127)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA F630206G17 gene Neighboring gene ATP synthase subunit g, mitochondrial-like Neighboring gene ferritin light chain 1 pseudogene Neighboring gene U7 snRNP-specific Sm-like protein LSM11 Neighboring gene tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0171, mKIAA0171

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    clathrin binding ISO
    Inferred from Sequence Orthology
    more info
     
    lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    clathrin coat assembly ISO
    Inferred from Sequence Orthology
    more info
     
    endocytosis IEA
    Inferred from Electronic Annotation
    more info
     
    vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    clathrin-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    clathrin interactor 1
    Names
    ENTH domain containing protein
    enthoprotin
    epsin 4
    epsin-related protein
    epsinR

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045520.4NP_001038985.2  clathrin interactor 1 isoform 1

      See identical proteins and their annotated locations for NP_001038985.2

      Status: VALIDATED

      Source sequence(s)
      AK143544, AK168991, AV318092, BX514666, BY628486, CN668129, DV653533
      Consensus CDS
      CCDS36130.1
      UniProtKB/TrEMBL
      Q3UPG6, Q5SUH7
      Related
      ENSMUSP00000104883.1, ENSMUST00000109260.1
      Conserved Domains (2) summary
      cd03571
      Location:23146
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      pfam15279
      Location:378563
      SOBP; Sine oculis-binding protein
    2. NM_001346760.2NP_001333689.1  clathrin interactor 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL645948
      Consensus CDS
      CCDS83796.1
      UniProtKB/TrEMBL
      Q5SUH6
    3. NM_001363484.1NP_001350413.1  clathrin interactor 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL645948
      Conserved Domains (3) summary
      cd03571
      Location:23146
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      pfam09606
      Location:467587
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam13634
      Location:329412
      Nucleoporin_FG; Nucleoporin FG repeat region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      45851932..45910625
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532838.3XP_006532901.1  clathrin interactor 1 isoform X1

      Related
      ENSMUSP00000104884.3, ENSMUST00000109261.9
      Conserved Domains (1) summary
      cd03571
      Location:23146
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
    2. XM_006532839.3XP_006532902.1  clathrin interactor 1 isoform X2

      Conserved Domains (1) summary
      cd03571
      Location:23146
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
    3. XM_006532840.3XP_006532903.1  clathrin interactor 1 isoform X3

      Conserved Domains (3) summary
      cd03571
      Location:23146
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      pfam09606
      Location:467587
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam13634
      Location:329412
      Nucleoporin_FG; Nucleoporin FG repeat region
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