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    Clint1 clathrin interactor 1 [ Mus musculus (house mouse) ]

    Gene ID: 216705, updated on 16-Oct-2021

    Summary

    Official Symbol
    Clint1provided by MGI
    Official Full Name
    clathrin interactor 1provided by MGI
    Primary source
    MGI:MGI:2144243
    See related
    Ensembl:ENSMUSG00000006169
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Enth; Epn4; AI642036; AW537616; C530049I24Rik; F630206G17Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 47.1), genital fat pad adult (RPKM 44.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Clint1 in Genome Data Viewer
    Location:
    11; 11 B1.1
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (45742756..45801452)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (45851944..45910625)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (45665466..45724127)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA F630206G17 gene Neighboring gene ferritin light chain 1 pseudogene Neighboring gene predicted gene, 53698 Neighboring gene U7 snRNP-specific Sm-like protein LSM11 Neighboring gene tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA0171, mKIAA0171

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables clathrin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables clathrin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phospholipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of clathrin vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    clathrin interactor 1
    Names
    ENTH domain containing protein
    enthoprotin
    epsin 4
    epsin-related protein
    epsinR

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045520.4NP_001038985.2  clathrin interactor 1 isoform 1

      See identical proteins and their annotated locations for NP_001038985.2

      Status: VALIDATED

      Source sequence(s)
      AK143544, AK168991, AV318092, BX514666, BY628486, CN668129, DV653533
      Consensus CDS
      CCDS36130.1
      UniProtKB/TrEMBL
      Q3UPG6, Q5SUH7
      Related
      ENSMUSP00000104883.2, ENSMUST00000109260.3
      Conserved Domains (2) summary
      cd03571
      Location:23146
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      pfam15279
      Location:378563
      SOBP; Sine oculis-binding protein
    2. NM_001346760.2NP_001333689.1  clathrin interactor 1 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL645948
      Consensus CDS
      CCDS83796.1
      UniProtKB/TrEMBL
      Q5SUH6
      Related
      ENSMUSP00000104884.4, ENSMUST00000109261.11
    3. NM_001363484.1NP_001350413.1  clathrin interactor 1 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL645948
      Conserved Domains (3) summary
      cd03571
      Location:23146
      ENTH_epsin; ENTH domain, Epsin family; The epsin (Eps15 interactor) N-terminal homology (ENTH) domain is an evolutionarily conserved protein module found primarily in proteins that participate in clathrin-mediated endocytosis. A set of proteins previously designated ...
      pfam09606
      Location:467587
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
      pfam13634
      Location:329412
      Nucleoporin_FG; Nucleoporin FG repeat region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      45742756..45801452
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532839.5XP_006532902.1  clathrin interactor 1 isoform X1

      Conserved Domains (2) summary
      cd16989
      Location:24149
      ENTH_EpsinR; Epsin N-Terminal Homology (ENTH) domain of Epsin-related protein
      pfam13634
      Location:329412
      Nucleoporin_FG; Nucleoporin FG repeat region
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