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    Papolg poly(A) polymerase gamma [ Mus musculus (house mouse) ]

    Gene ID: 216578, updated on 23-Jun-2021

    Summary

    Official Symbol
    Papolgprovided by MGI
    Official Full Name
    poly(A) polymerase gammaprovided by MGI
    Primary source
    MGI:MGI:2442119
    See related
    Ensembl:ENSMUSG00000020273
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9630006B20Rik
    Expression
    Ubiquitous expression in CNS E14 (RPKM 4.0), CNS E11.5 (RPKM 4.0) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Papolg in Genome Data Viewer
    Location:
    11; 11 A3.2
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (23810145..23845292, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (23860145..23895293, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (23762646..23795270, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene reticuloendotheliosis oncogene Neighboring gene predicted gene, 39612 Neighboring gene predicted gene 12061 Neighboring gene RIKEN cDNA A830031A19 gene Neighboring gene uncharacterized LOC118567902 Neighboring gene B cell CLL/lymphoma 11A (zinc finger protein) Neighboring gene RIKEN cDNA 4930538E20 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables polynucleotide adenylyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables polynucleotide adenylyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in RNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in RNA polyadenylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mRNA polyadenylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    poly(A) polymerase gamma
    Names
    PAP-gamma
    SRP 3'-adenylating protein
    SRP RNA 3'-adenylating enzyme
    SRP RNA-adenylating enzyme
    polynucleotide adenylyltransferase gamma
    signal recognition particle RNA-adenylating enzyme
    NP_766143.2
    XP_006514716.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172555.2NP_766143.2  poly(A) polymerase gamma

      See identical proteins and their annotated locations for NP_766143.2

      Status: VALIDATED

      Source sequence(s)
      AK035810, BC023030, CJ075859, DQ103505
      Consensus CDS
      CCDS24481.1
      UniProtKB/Swiss-Prot
      Q6PCL9
      UniProtKB/TrEMBL
      Q8R1V7
      Related
      ENSMUSP00000020513.4, ENSMUST00000020513.10
      Conserved Domains (3) summary
      PTZ00418
      Location:3569
      PTZ00418; Poly(A) polymerase; Provisional
      pfam04926
      Location:365504
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:20363
      PAP_central; Poly(A) polymerase central domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      23810145..23845292 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514653.5XP_006514716.1  poly(A) polymerase gamma isoform X1

      Conserved Domains (3) summary
      PTZ00449
      Location:481715
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      pfam04926
      Location:357495
      PAP_RNA-bind; Poly(A) polymerase predicted RNA binding domain
      pfam04928
      Location:12354
      PAP_central; Poly(A) polymerase central domain

    RNA

    1. XR_380964.4 RNA Sequence

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