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    Tmem259 transmembrane protein 259 [ Mus musculus (house mouse) ]

    Gene ID: 216157, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tmem259provided by MGI
    Official Full Name
    transmembrane protein 259provided by MGI
    Primary source
    MGI:MGI:2177957
    See related
    Ensembl:ENSMUSG00000013858
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    memb; ORF61; R32184_3; mFLJ00277; AC087114.7gm2
    Expression
    Ubiquitous expression in adrenal adult (RPKM 266.2), duodenum adult (RPKM 252.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Tmem259 in Genome Data Viewer
    Location:
    10; 10 C1
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (79812954..79820159, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (79977120..79984325, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (79439865..79447075, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene AT rich interactive domain 3A (BRIGHT-like) Neighboring gene WD repeat domain 18 Neighboring gene glutamate receptor, ionotropic, NMDA3B Neighboring gene predicted gene, 26243 Neighboring gene calponin 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ00277, MGC90890, AC087114.7gm12

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003949.4NP_001003949.2  membralin isoform 2

      See identical proteins and their annotated locations for NP_001003949.2

      Status: VALIDATED

      Source sequence(s)
      AC151846, BE947335, BQ571954, BQ572278, CO044817, CX205815
      Consensus CDS
      CCDS24002.1
      UniProtKB/Swiss-Prot
      Q8CIV2
      Related
      ENSMUSP00000056792.8, ENSMUST00000052885.14
      Conserved Domains (1) summary
      pfam09746
      Location:34393
      Membralin; Tumour-associated protein
    2. NM_001359632.1NP_001346561.1  membralin isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC151846, BE947335, BQ571954, BQ572278, BQ748980, CO044817, CX205815
      Related
      ENSMUSP00000119572.2, ENSMUST00000124536.2
      Conserved Domains (2) summary
      pfam09746
      Location:35417
      Membralin; tumor-associated protein
      cl28033
      Location:484596
      Herpes_ICP4_C; Herpesvirus ICP4-like protein C-terminal region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      79812954..79820159 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006513491.1XP_006513554.1  membralin isoform X1

      See identical proteins and their annotated locations for XP_006513554.1

      Conserved Domains (2) summary
      PHA03307
      Location:443555
      PHA03307; transcriptional regulator ICP4; Provisional
      pfam09746
      Location:34376
      Membralin; tumor-associated protein
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