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    Polrmt polymerase (RNA) mitochondrial (DNA directed) [ Mus musculus (house mouse) ]

    Gene ID: 216151, updated on 23-Jun-2021

    Summary

    Official Symbol
    Polrmtprovided by MGI
    Official Full Name
    polymerase (RNA) mitochondrial (DNA directed)provided by MGI
    Primary source
    MGI:MGI:1915843
    See related
    Ensembl:ENSMUSG00000020329
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4932416K13; 1110018N15Rik
    Expression
    Ubiquitous expression in adrenal adult (RPKM 28.6), ovary adult (RPKM 26.0) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Polrmt in Genome Data Viewer
    Location:
    10; 10 C1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (79571951..79582436, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (79736125..79746604, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (79198870..79209326, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene basigin Neighboring gene hyperpolarization-activated, cyclic nucleotide-gated K+ 2 Neighboring gene fibroblast growth factor 22 Neighboring gene ring finger protein 126

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (3)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC118526

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-directed 5'-3' RNA polymerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables DNA-directed 5'-3' RNA polymerase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables mitochondrial promoter sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in mitochondrial transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitochondrial transcription ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of mitochondrial DNA-directed RNA polymerase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial nucleoid ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    DNA-directed RNA polymerase, mitochondrial
    Names
    mitochondrial DNA-directed RNA polymerase
    mtRPOL
    NP_766139.2
    XP_030100878.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172551.3NP_766139.2  DNA-directed RNA polymerase, mitochondrial precursor

      See identical proteins and their annotated locations for NP_766139.2

      Status: VALIDATED

      Source sequence(s)
      AK030039, AK042071, AK053356
      Consensus CDS
      CCDS23987.1
      UniProtKB/Swiss-Prot
      Q8BKF1
      UniProtKB/TrEMBL
      Q3U3J3, Q3V3C0
      Related
      ENSMUSP00000020580.7, ENSMUST00000020580.13
      Conserved Domains (4) summary
      PHA00452
      Location:4371207
      PHA00452; T3/T7-like RNA polymerase
      sd00004
      Location:233262
      PPR; PPR repeat [structural motif]
      pfam00940
      Location:8021206
      RNA_pol; DNA-dependent RNA polymerase
      pfam14700
      Location:374674
      RPOL_N; DNA-directed RNA polymerase N-terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      79571951..79582436 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030245018.2XP_030100878.1  DNA-directed RNA polymerase, mitochondrial isoform X1

      Conserved Domains (3) summary
      sd00004
      Location:233262
      PPR; PPR repeat [structural motif]
      pfam00940
      Location:8021236
      RNA_pol; DNA-dependent RNA polymerase
      pfam14700
      Location:375675
      RPOL_N; DNA-directed RNA polymerase N-terminal

    RNA

    1. XR_871707.4 RNA Sequence

      Related
      ENSMUST00000162694.8
    2. XR_003948668.2 RNA Sequence

      Related
      ENSMUST00000159082.8
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