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    Rhot2 ras homolog family member T2 [ Mus musculus (house mouse) ]

    Gene ID: 214952, updated on 17-Aug-2021

    Summary

    Official Symbol
    Rhot2provided by MGI
    Official Full Name
    ras homolog family member T2provided by MGI
    Primary source
    MGI:MGI:2384892
    See related
    Ensembl:ENSMUSG00000025733
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mi; Arh; Arht2; Miro2
    Expression
    Ubiquitous expression in adrenal adult (RPKM 113.1), colon adult (RPKM 76.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rhot2 in Genome Data Viewer
    Location:
    17 A3.3; 17 12.93 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (26057431..26063499, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (25838457..25844525, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (25975783..25981796, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene jumonji domain containing 8 Neighboring gene microRNA 3082 Neighboring gene STIP1 homology and U-Box containing protein 1 Neighboring gene rhomboid like 1 Neighboring gene WD repeat domain 90 Neighboring gene MAPK regulated corepressor interacting protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Potential readthrough

    Included gene: Rhbdl1

    Homology

    Clone Names

    • MGC31216

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in cellular homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial outer membrane permeabilization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitochondrion transport along microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitochondrion transport along microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitochondrion organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    mitochondrial Rho GTPase 2
    Names
    mitochondrial Rho 2
    ras homolog gene family, member T2
    NP_001351879.1
    NP_666111.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001364950.1NP_001351879.1  mitochondrial Rho GTPase 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC159277
      Conserved Domains (5) summary
      cd01892
      Location:412589
      Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
      cd01893
      Location:11167
      Miro1; Mitochondrial Rho family 1 (Miro1), N-terminal
      pfam08355
      Location:339406
      EF_assoc_1; EF hand associated
      pfam08356
      Location:218303
      EF_assoc_2; EF hand associated
      pfam13499
      Location:307336
      EF-hand_7; EF-hand domain pair
    2. NM_145999.3NP_666111.1  mitochondrial Rho GTPase 2 isoform 1

      See identical proteins and their annotated locations for NP_666111.1

      Status: VALIDATED

      Source sequence(s)
      AC159277, AY311390
      Consensus CDS
      CCDS37505.1
      UniProtKB/Swiss-Prot
      Q8JZN7
      Related
      ENSMUSP00000044639.10, ENSMUST00000043897.16
      Conserved Domains (5) summary
      smart00174
      Location:7169
      RHO; Rho (Ras homology) subfamily of Ras-like small GTPases
      cd01892
      Location:414591
      Miro2; Mitochondrial Rho family 2 (Miro2), C-terminal
      cd01893
      Location:3169
      Miro1; Mitochondrial Rho family 1 (Miro1), N-terminal
      pfam08355
      Location:341408
      EF_assoc_1; EF hand associated
      pfam08356
      Location:221301
      EF_assoc_2; EF hand associated

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      26057431..26063499 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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