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    Csnk1g1 casein kinase 1, gamma 1 [ Mus musculus (house mouse) ]

    Gene ID: 214897, updated on 26-Sep-2022

    Summary

    Official Symbol
    Csnk1g1provided by MGI
    Official Full Name
    casein kinase 1, gamma 1provided by MGI
    Primary source
    MGI:MGI:2660884
    See related
    Ensembl:ENSMUSG00000032384 AllianceGenome:MGI:2660884
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9130020E21Rik
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in several processes, including Wnt signaling pathway; positive regulation of canonical Wnt signaling pathway; and protein phosphorylation. Predicted to act upstream of or within phosphorylation. Predicted to be located in cytosol. Predicted to be active in cytoplasm; nucleus; and plasma membrane. Is expressed in central nervous system; genitourinary system; retina; and skin. Orthologous to human CSNK1G1 (casein kinase 1 gamma 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 3.9), whole brain E14.5 (RPKM 3.6) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Csnk1g1 in Genome Data Viewer
    Location:
    9; 9 C
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (65816235..65952297)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (65908968..66045015)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene thyroid hormone receptor interactor 4 Neighboring gene predicted gene, 53535 Neighboring gene PCNA clamp associated factor Neighboring gene predicted gene, 23248 Neighboring gene predicted gene, 22657 Neighboring gene peptidylprolyl isomerase B Neighboring gene sorting nexin 22 Neighboring gene sorting nexin 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (2) 
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein serine/threonine kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in peptidyl-serine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in peptidyl-serine phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of canonical Wnt signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein autophosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    casein kinase I isoform gamma-1; casein kinase I
    Names
    CKI-gamma 1
    casein kinase I, gamma 1
    NP_775277.2
    XP_006511071.1
    XP_011241005.1
    XP_011241006.1
    XP_011241007.1
    XP_011241008.1
    XP_011241009.1
    XP_011241010.1
    XP_011241011.1
    XP_011241012.1
    XP_011241014.1
    XP_030100085.1
    XP_030100087.1
    XP_036010717.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173185.2NP_775277.2  casein kinase I isoform gamma-1

      See identical proteins and their annotated locations for NP_775277.2

      Status: VALIDATED

      Source sequence(s)
      AC112676, AK090262, BC064645
      Consensus CDS
      CCDS23300.1
      UniProtKB/Swiss-Prot
      E9QPK6, Q8BTH8
      UniProtKB/TrEMBL
      Q6P2B2
      Related
      ENSMUSP00000034949.4, ENSMUST00000034949.10
      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331418
      CK1gamma_C; Casein kinase 1 gamma C terminal

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      65816235..65952297
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006511008.4XP_006511071.1  casein kinase I isoform X1

      See identical proteins and their annotated locations for XP_006511071.1

      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331429
      CK1gamma_C; Casein kinase 1 gamma C terminal
    2. XM_030244227.2XP_030100087.1  casein kinase I isoform X2

      UniProtKB/Swiss-Prot
      E9QPK6
      Related
      ENSMUSP00000145947.2, ENSMUST00000206594.2
      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331418
      CK1gamma_C; Casein kinase 1 gamma C terminal
    3. XM_011242704.2XP_011241006.1  casein kinase I isoform X1

      See identical proteins and their annotated locations for XP_011241006.1

      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331429
      CK1gamma_C; Casein kinase 1 gamma C terminal
    4. XM_011242703.2XP_011241005.1  casein kinase I isoform X1

      See identical proteins and their annotated locations for XP_011241005.1

      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331429
      CK1gamma_C; Casein kinase 1 gamma C terminal
    5. XM_011242709.3XP_011241011.1  casein kinase I isoform X3

      See identical proteins and their annotated locations for XP_011241011.1

      UniProtKB/TrEMBL
      Q6P2B2
      Related
      ENSMUSP00000113160.2, ENSMUST00000117849.3
      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331381
      CK1gamma_C; Casein kinase 1 gamma C terminal
    6. XM_011242710.2XP_011241012.1  casein kinase I isoform X4

      UniProtKB/TrEMBL
      A0A0U1RNW0
      Related
      ENSMUSP00000145724.2, ENSMUST00000205379.2
      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331381
      CK1gamma_C; Casein kinase 1 gamma C terminal
    7. XM_011242707.2XP_011241009.1  casein kinase I isoform X1

      See identical proteins and their annotated locations for XP_011241009.1

      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331429
      CK1gamma_C; Casein kinase 1 gamma C terminal
    8. XM_011242706.2XP_011241008.1  casein kinase I isoform X1

      See identical proteins and their annotated locations for XP_011241008.1

      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331429
      CK1gamma_C; Casein kinase 1 gamma C terminal
    9. XM_011242705.2XP_011241007.1  casein kinase I isoform X1

      See identical proteins and their annotated locations for XP_011241007.1

      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331429
      CK1gamma_C; Casein kinase 1 gamma C terminal
    10. XM_011242712.3XP_011241014.1  casein kinase I isoform X5

      UniProtKB/TrEMBL
      A0A0U1RPD7
      Related
      ENSMUSP00000145938.2, ENSMUST00000130798.3
      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331388
      CK1gamma_C; Casein kinase 1 gamma C terminal
    11. XM_011242708.3XP_011241010.1  casein kinase I isoform X2

      See identical proteins and their annotated locations for XP_011241010.1

      UniProtKB/Swiss-Prot
      E9QPK6, Q8BTH8
      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331418
      CK1gamma_C; Casein kinase 1 gamma C terminal
    12. XM_030244225.2XP_030100085.1  casein kinase I isoform X1

      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331429
      CK1gamma_C; Casein kinase 1 gamma C terminal
    13. XM_036154824.1XP_036010717.1  casein kinase I isoform X1

      Conserved Domains (2) summary
      cd14126
      Location:43331
      STKc_CK1_gamma; Catalytic domain of the Serine/Threonine protein kinase, Casein Kinase 1 gamma
      pfam12605
      Location:331429
      CK1gamma_C; Casein kinase 1 gamma C terminal

    RNA

    1. XR_003947839.2 RNA Sequence