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    Tdrd5 tudor domain containing 5 [ Mus musculus (house mouse) ]

    Gene ID: 214575, updated on 17-Aug-2021

    Summary

    Official Symbol
    Tdrd5provided by MGI
    Official Full Name
    tudor domain containing 5provided by MGI
    Primary source
    MGI:MGI:2684949
    See related
    Ensembl:ENSMUSG00000060985
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm103
    Expression
    Biased expression in testis adult (RPKM 8.7), thymus adult (RPKM 3.7) and 3 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Tdrd5 in Genome Data Viewer
    Location:
    1; 1 G3
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (156082866..156131874, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (156255296..156304304, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (158185426..158233479, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 163, member A Neighboring gene predicted gene, 30472 Neighboring gene nephrosis 2, podocin Neighboring gene axonemal dynein light chain domain containing 1 Neighboring gene ribosomal protein L35 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in DNA methylation involved in gamete generation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in P granule organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in germ cell development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in spermatid development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within spermatogenesis IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in chromatoid body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in pi-body IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    tudor domain-containing protein 5
    Names
    tudor domain containing protein 5

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001134741.1NP_001128213.1  tudor domain-containing protein 5 isoform 1

      See identical proteins and their annotated locations for NP_001128213.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK132674, BC099972, DV655037, DV659775
      Consensus CDS
      CCDS56647.1
      UniProtKB/Swiss-Prot
      Q5VCS6
      Related
      ENSMUSP00000137298.2, ENSMUST00000121146.10
      Conserved Domains (5) summary
      cd04508
      Location:537583
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      cd09975
      Location:127196
      LOTUS_2_TDRD5; The second LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09976
      Location:292365
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      pfam00567
      Location:483602
      TUDOR; Tudor domain
    2. NM_001277730.1NP_001264659.1  tudor domain-containing protein 5 isoform 2

      See identical proteins and their annotated locations for NP_001264659.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, and uses two alternate splice sites that result in the loss of an in-frame segment in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AK132674, BC099972, DV659775
      UniProtKB/Swiss-Prot
      Q5VCS6
      Conserved Domains (3) summary
      cd09976
      Location:197270
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      pfam00567
      Location:388507
      TUDOR; Tudor domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      156082866..156131874 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006496733.3XP_006496796.1  tudor domain-containing protein 5 isoform X8

      See identical proteins and their annotated locations for XP_006496796.1

      UniProtKB/Swiss-Prot
      Q5VCS6
      Conserved Domains (3) summary
      cd09976
      Location:197270
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      pfam00567
      Location:388507
      TUDOR; Tudor domain
    2. XM_006496731.3XP_006496794.1  tudor domain-containing protein 5 isoform X6

      UniProtKB/TrEMBL
      J3QPB7
      Related
      ENSMUSP00000137182.2, ENSMUST00000167528.9
      Conserved Domains (3) summary
      cd09976
      Location:215288
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      pfam00567
      Location:406525
      TUDOR; Tudor domain
    3. XM_006496728.3XP_006496791.1  tudor domain-containing protein 5 isoform X3

      Conserved Domains (4) summary
      cd09975
      Location:127196
      LOTUS_2_TDRD5; The second LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09976
      Location:274347
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      pfam00567
      Location:465584
      TUDOR; Tudor domain
    4. XM_006496726.4XP_006496789.1  tudor domain-containing protein 5 isoform X1

      Conserved Domains (4) summary
      cd09975
      Location:127196
      LOTUS_2_TDRD5; The second LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09976
      Location:292365
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      pfam00567
      Location:482601
      TUDOR; Tudor domain
    5. XM_006496727.4XP_006496790.1  tudor domain-containing protein 5 isoform X2

      Conserved Domains (4) summary
      cd09975
      Location:127196
      LOTUS_2_TDRD5; The second LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09976
      Location:292365
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      pfam00567
      Location:483602
      TUDOR; Tudor domain
    6. XM_006496729.4XP_006496792.1  tudor domain-containing protein 5 isoform X4

      Conserved Domains (4) summary
      cd09975
      Location:127196
      LOTUS_2_TDRD5; The second LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09976
      Location:292365
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      pfam00567
      Location:483602
      TUDOR; Tudor domain
    7. XM_006496734.1XP_006496797.1  tudor domain-containing protein 5 isoform X9

      Conserved Domains (3) summary
      cd09975
      Location:2493
      LOTUS_2_TDRD5; The second LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09976
      Location:189262
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      pfam00567
      Location:380499
      TUDOR; Tudor domain
    8. XM_006496730.3XP_006496793.1  tudor domain-containing protein 5 isoform X5

      Conserved Domains (4) summary
      cd09975
      Location:127196
      LOTUS_2_TDRD5; The second LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09976
      Location:292365
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      pfam00567
      Location:483602
      TUDOR; Tudor domain
    9. XM_006496732.3XP_006496795.1  tudor domain-containing protein 5 isoform X7

      Conserved Domains (4) summary
      cd09975
      Location:127196
      LOTUS_2_TDRD5; The second LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09976
      Location:292365
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      pfam00567
      Location:483602
      TUDOR; Tudor domain
    10. XM_030252864.1XP_030108724.1  tudor domain-containing protein 5 isoform X11

      Conserved Domains (4) summary
      cd09975
      Location:127196
      LOTUS_2_TDRD5; The second LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09976
      Location:292365
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd20419
      Location:484601
      Tudor_TDRD5; Tudor domain found in Tudor domain-containing protein 5 (TDRD5) and similar proteins
    11. XM_011238780.3XP_011237082.1  tudor domain-containing protein 5 isoform X10

      Conserved Domains (4) summary
      cd09975
      Location:127196
      LOTUS_2_TDRD5; The second LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09976
      Location:292365
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      pfam00567
      Location:483602
      TUDOR; Tudor domain
    12. XM_036163492.1XP_036019385.1  tudor domain-containing protein 5 isoform X11

      Conserved Domains (4) summary
      cd09975
      Location:127196
      LOTUS_2_TDRD5; The second LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09976
      Location:292365
      LOTUS_3_TDRD5; The third LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd09985
      Location:498
      LOTUS_1_TDRD5; The first LOTUS domain on Tudor-containing protein 5 (TDRD5)
      cd20419
      Location:484601
      Tudor_TDRD5; Tudor domain found in Tudor domain-containing protein 5 (TDRD5) and similar proteins

    RNA

    1. XR_004941506.1 RNA Sequence

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