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    Tut7 terminal uridylyl transferase 7 [ Mus musculus (house mouse) ]

    Gene ID: 214290, updated on 19-Jul-2021

    Summary

    Official Symbol
    Tut7provided by MGI
    Official Full Name
    terminal uridylyl transferase 7provided by MGI
    Primary source
    MGI:MGI:2387179
    See related
    Ensembl:ENSMUSG00000035248
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tent3; Tent3b; Zcchc6; AA420405; 6030448M23Rik
    Expression
    Ubiquitous expression in liver E14 (RPKM 11.4), liver E14.5 (RPKM 9.7) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Tut7 in Genome Data Viewer
    Location:
    13; 13 B2
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (59919690..59971060, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (59771876..59823169, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (59873240..59924508, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700014D04 gene Neighboring gene iron-sulfur cluster assembly 1 Neighboring gene ethanol decreased 2 Neighboring gene predicted gene, 19866 Neighboring gene predicted gene, 35143

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (3)  1 citation
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC38585

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA uridylyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA uridylyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables miRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotidyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables uridylyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables uridylyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in RNA 3' uridylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in RNA 3' uridylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in RNA 3' uridylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in RNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in RNA 3'-end processing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in miRNA metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of transposition, RNA-mediated ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in oocyte maturation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in polyuridylation-dependent mRNA catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in pre-miRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    terminal uridylyltransferase 7
    Names
    TUTase 7
    zinc finger CCHC domain-containing protein 6
    zinc finger, CCHC domain containing 6
    NP_001360891.1
    NP_001360892.1
    NP_001360893.1
    NP_705766.3
    XP_006517270.1
    XP_006517272.1
    XP_036013864.1
    XP_036013865.1
    XP_036013866.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001373962.1NP_001360891.1  terminal uridylyltransferase 7 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC125350, AC134869
      Conserved Domains (6) summary
      smart00343
      Location:14481464
      ZnF_C2HC; zinc finger
      COG5260
      Location:9751306
      TRF4; DNA polymerase sigma [Replication, recombination and repair]
      TIGR00927
      Location:673910
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam03828
      Location:550599
      PAP_assoc; Cid1 family poly A polymerase
      pfam16631
      Location:13651446
      TUTF7_u4; Unstructured region 4 on terminal uridylyltransferase 7
      pfam19088
      Location:205539
      TUTase; TUTase nucleotidyltransferase domain
    2. NM_001373963.1NP_001360892.1  terminal uridylyltransferase 7 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC125350, AC134869
      Conserved Domains (6) summary
      smart00343
      Location:14481464
      ZnF_C2HC; zinc finger
      COG5260
      Location:9751306
      TRF4; DNA polymerase sigma [Replication, recombination and repair]
      TIGR00927
      Location:673910
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam03828
      Location:550599
      PAP_assoc; Cid1 family poly A polymerase
      pfam16631
      Location:13651446
      TUTF7_u4; Unstructured region 4 on terminal uridylyltransferase 7
      pfam19088
      Location:205539
      TUTase; TUTase nucleotidyltransferase domain
    3. NM_001373964.1NP_001360893.1  terminal uridylyltransferase 7 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC125350, AC134869
      Conserved Domains (6) summary
      smart00343
      Location:14481464
      ZnF_C2HC; zinc finger
      COG5260
      Location:9751306
      TRF4; DNA polymerase sigma [Replication, recombination and repair]
      TIGR00927
      Location:673910
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam03828
      Location:550599
      PAP_assoc; Cid1 family poly A polymerase
      pfam16631
      Location:13651446
      TUTF7_u4; Unstructured region 4 on terminal uridylyltransferase 7
      pfam19088
      Location:205539
      TUTase; TUTase nucleotidyltransferase domain
    4. NM_153538.3NP_705766.3  terminal uridylyltransferase 7 isoform 2

      See identical proteins and their annotated locations for NP_705766.3

      Status: VALIDATED

      Source sequence(s)
      BC043111, CB526652, CJ054882
      Consensus CDS
      CCDS36689.1
      UniProtKB/Swiss-Prot
      Q5BLK4
      UniProtKB/TrEMBL
      E9PUA2
      Related
      ENSMUSP00000071623.5, ENSMUST00000071703.6
      Conserved Domains (6) summary
      smart00343
      Location:14481464
      ZnF_C2HC; zinc finger
      COG5260
      Location:9751306
      TRF4; DNA polymerase sigma [Replication, recombination and repair]
      TIGR00927
      Location:673910
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam03828
      Location:550599
      PAP_assoc; Cid1 family poly A polymerase
      pfam16631
      Location:13651446
      TUTF7_u4; Unstructured region 4 on terminal uridylyltransferase 7
      pfam19088
      Location:205539
      TUTase; TUTase nucleotidyltransferase domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      59919690..59971060 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157972.1XP_036013865.1  terminal uridylyltransferase 7 isoform X2

      Conserved Domains (6) summary
      smart00343
      Location:14481464
      ZnF_C2HC; zinc finger
      COG5260
      Location:9751306
      TRF4; DNA polymerase sigma [Replication, recombination and repair]
      TIGR00927
      Location:673910
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam03828
      Location:550599
      PAP_assoc; Cid1 family poly A polymerase
      pfam16631
      Location:13651446
      TUTF7_u4; Unstructured region 4 on terminal uridylyltransferase 7
      pfam19088
      Location:205539
      TUTase; TUTase nucleotidyltransferase domain
    2. XM_036157971.1XP_036013864.1  terminal uridylyltransferase 7 isoform X1

      Conserved Domains (6) summary
      smart00343
      Location:14481464
      ZnF_C2HC; zinc finger
      COG5260
      Location:9751306
      TRF4; DNA polymerase sigma [Replication, recombination and repair]
      TIGR00927
      Location:673910
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam03828
      Location:550599
      PAP_assoc; Cid1 family poly A polymerase
      pfam16631
      Location:13651446
      TUTF7_u4; Unstructured region 4 on terminal uridylyltransferase 7
      pfam19088
      Location:205539
      TUTase; TUTase nucleotidyltransferase domain
    3. XM_006517209.3XP_006517272.1  terminal uridylyltransferase 7 isoform X3

      See identical proteins and their annotated locations for XP_006517272.1

      UniProtKB/TrEMBL
      E9PUA2
      Conserved Domains (6) summary
      smart00343
      Location:14481464
      ZnF_C2HC; zinc finger
      COG5260
      Location:9751306
      TRF4; DNA polymerase sigma [Replication, recombination and repair]
      TIGR00927
      Location:673910
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam03828
      Location:550599
      PAP_assoc; Cid1 family poly A polymerase
      pfam16631
      Location:13651446
      TUTF7_u4; Unstructured region 4 on terminal uridylyltransferase 7
      pfam19088
      Location:205539
      TUTase; TUTase nucleotidyltransferase domain
    4. XM_006517207.3XP_006517270.1  terminal uridylyltransferase 7 isoform X1

      See identical proteins and their annotated locations for XP_006517270.1

      Conserved Domains (6) summary
      smart00343
      Location:14481464
      ZnF_C2HC; zinc finger
      COG5260
      Location:9751306
      TRF4; DNA polymerase sigma [Replication, recombination and repair]
      TIGR00927
      Location:673910
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam03828
      Location:550599
      PAP_assoc; Cid1 family poly A polymerase
      pfam16631
      Location:13651446
      TUTF7_u4; Unstructured region 4 on terminal uridylyltransferase 7
      pfam19088
      Location:205539
      TUTase; TUTase nucleotidyltransferase domain
    5. XM_036157973.1XP_036013866.1  terminal uridylyltransferase 7 isoform X3

      Conserved Domains (6) summary
      smart00343
      Location:14481464
      ZnF_C2HC; zinc finger
      COG5260
      Location:9751306
      TRF4; DNA polymerase sigma [Replication, recombination and repair]
      TIGR00927
      Location:673910
      2A1904; K+-dependent Na+/Ca+ exchanger
      pfam03828
      Location:550599
      PAP_assoc; Cid1 family poly A polymerase
      pfam16631
      Location:13651446
      TUTF7_u4; Unstructured region 4 on terminal uridylyltransferase 7
      pfam19088
      Location:205539
      TUTase; TUTase nucleotidyltransferase domain

    RNA

    1. XR_003950443.2 RNA Sequence

    2. XR_004938011.1 RNA Sequence

    3. XR_004938012.1 RNA Sequence

    4. XR_003950441.2 RNA Sequence

    5. XR_003950442.1 RNA Sequence

    6. XR_004938010.1 RNA Sequence

      Related
      ENSMUST00000224480.2
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