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    Skp1a S-phase kinase-associated protein 1A [ Mus musculus (house mouse) ]

    Gene ID: 21402, updated on 5-Aug-2018

    Summary

    Official Symbol
    Skp1aprovided by MGI
    Official Full Name
    S-phase kinase-associated protein 1Aprovided by MGI
    Primary source
    MGI:MGI:103575
    See related
    Ensembl:ENSMUSG00000036309 Vega:OTTMUSG00000005625
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    OCP2; SKP1; p19A; 15kDa; EMC19; OCP-II; Tceb1l; p19Skp1; 2610043E24Rik; 2610206H23Rik
    Expression
    Broad expression in CNS E18 (RPKM 68.9), CNS E11.5 (RPKM 64.4) and 22 other tissues See more
    Orthologs

    Genomic context

    See Skp1a in Genome Data Viewer
    Location:
    11 B1.3; 11 31.86 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (52230522..52246858)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (52045497..52060360)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene predicted gene 12206 Neighboring gene olfactory receptor 1371 Neighboring gene transcription factor 7, T cell specific Neighboring gene predicted gene, 30217

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    beta-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    cullin family protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    contributes_to ubiquitin-protein transferase activity IC
    Inferred by Curator
    more info
    PubMed 
    ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Cul7-RING ubiquitin ligase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Cul7-RING ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    colocalizes_with PcG protein complex ISO
    Inferred from Sequence Orthology
    more info
     
    SCF ubiquitin ligase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    SCF ubiquitin ligase complex ISO
    Inferred from Sequence Orthology
    more info
     
    centrosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    S-phase kinase-associated protein 1
    Names
    cyclin-A/CDK2-associated protein p19
    NP_035673.3
    XP_006532849.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011543.4NP_035673.3  S-phase kinase-associated protein 1

      See identical proteins and their annotated locations for NP_035673.3

      Status: VALIDATED

      Source sequence(s)
      AK012498, AK078330, BU841654
      Consensus CDS
      CCDS24669.1
      UniProtKB/Swiss-Prot
      Q9WTX5
      UniProtKB/TrEMBL
      Q5SUR3
      Related
      ENSMUSP00000038744.5, OTTMUSP00000005802, ENSMUST00000037324.11, OTTMUST00000012512
      Conserved Domains (1) summary
      cl27564
      Location:1163
      Skp1; Skp1 family, dimerisation domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      52230522..52246858
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006532786.2XP_006532849.1  S-phase kinase-associated protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006532849.1

      UniProtKB/Swiss-Prot
      Q9WTX5
      UniProtKB/TrEMBL
      Q5SUR3
      Conserved Domains (1) summary
      cl27564
      Location:1163
      Skp1; Skp1 family, dimerisation domain
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