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    Ccdc186 coiled-coil domain containing 186 [ Mus musculus (house mouse) ]

    Gene ID: 213993, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ccdc186provided by MGI
    Official Full Name
    coiled-coil domain containing 186provided by MGI
    Primary source
    MGI:MGI:2445022
    See related
    Ensembl:ENSMUSG00000035173
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Otg; Otg1; AI159700; 1810028B20Rik; A630007B06Rik
    Expression
    Ubiquitous expression in cerebellum adult (RPKM 5.0), CNS E14 (RPKM 4.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Ccdc186 in Genome Data Viewer
    Location:
    19; 19 D2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (56775917..56810631, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (56787485..56822199, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (56865453..56888173, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene adrenergic receptor, beta 1 Neighboring gene predicted gene, 32718 Neighboring gene rp1 MIF pseudogene Neighboring gene tudor domain containing 1 Neighboring gene von Willebrand factor A domain containing 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables small GTPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in trans-Golgi network IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    coiled-coil domain-containing protein 186
    Names
    oocyte-testis gene 1 protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_170757.2NP_739563.1  coiled-coil domain-containing protein 186

      See identical proteins and their annotated locations for NP_739563.1

      Status: VALIDATED

      Source sequence(s)
      AC158549
      Consensus CDS
      CCDS29921.1
      UniProtKB/Swiss-Prot
      Q8C9S4
      Related
      ENSMUSP00000113457.2, ENSMUST00000118592.8
      Conserved Domains (1) summary
      pfam09728
      Location:315645
      Taxilin; Myosin-like coiled-coil protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      56775917..56810631 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006526852.2XP_006526915.1  coiled-coil domain-containing protein 186 isoform X1

      Conserved Domains (2) summary
      COG1196
      Location:159533
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:42324
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
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