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    Tbrg4 transforming growth factor beta regulated gene 4 [ Mus musculus (house mouse) ]

    Gene ID: 21379, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tbrg4provided by MGI
    Official Full Name
    transforming growth factor beta regulated gene 4provided by MGI
    Primary source
    MGI:MGI:1100868
    See related
    Ensembl:ENSMUSG00000000384
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cp; Cpr2; Tb-12; R74877; AA120735; AA408001; AI527316; 2310042P22Rik
    Expression
    Ubiquitous expression in colon adult (RPKM 29.8), large intestine adult (RPKM 26.5) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Tbrg4 in Genome Data Viewer
    Location:
    11; 11 A1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (6565598..6576089, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (6615598..6626084, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (6515601..6526070, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene cerebral cavernous malformation 2 Neighboring gene NAC alpha domain containing Neighboring gene predicted gene, 24313 Neighboring gene small nucleolar RNA, H/ACA box 5C Neighboring gene whey acidic protein Neighboring gene predicted gene 11978 Neighboring gene receptor (calcitonin) activity modifying protein 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • mKIAA0948

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mRNA metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in mitochondrial RNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in mitochondrial mRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitochondrial mRNA stability IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in regulation of mitochondrial mRNA stability ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrial matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in ribonucleoprotein granule IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    FAST kinase domain-containing protein 4
    Names
    cell cycle progression 2 protein
    protein TBRG4
    transforming growth factor beta regulator 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130457.2NP_001123929.1  FAST kinase domain-containing protein 4 isoform 1

      See identical proteins and their annotated locations for NP_001123929.1

      Status: VALIDATED

      Source sequence(s)
      BC031910, BY784127
      Consensus CDS
      CCDS24423.1
      UniProtKB/Swiss-Prot
      Q91YM4
      Related
      ENSMUSP00000140835.2, ENSMUST00000189268.7
      Conserved Domains (3) summary
      smart00952
      Location:562619
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:368437
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:453534
      FAST_2; FAST kinase-like protein, subdomain 2
    2. NM_001362713.1NP_001349642.1  FAST kinase domain-containing protein 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL603787
      Consensus CDS
      CCDS24423.1
      Conserved Domains (3) summary
      smart00952
      Location:562619
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:368437
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:453534
      FAST_2; FAST kinase-like protein, subdomain 2
    3. NM_001362714.1NP_001349643.1  FAST kinase domain-containing protein 4 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL603787
      Consensus CDS
      CCDS24423.1
      Conserved Domains (3) summary
      smart00952
      Location:562619
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:368437
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:453534
      FAST_2; FAST kinase-like protein, subdomain 2
    4. NM_001362715.1NP_001349644.1  FAST kinase domain-containing protein 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL603787
      Conserved Domains (3) summary
      smart00952
      Location:275332
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:81150
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:166247
      FAST_2; FAST kinase-like protein, subdomain 2
    5. NM_001362716.1NP_001349645.1  FAST kinase domain-containing protein 4 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AL603787
      Conserved Domains (3) summary
      smart00952
      Location:275332
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:81150
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:166247
      FAST_2; FAST kinase-like protein, subdomain 2
    6. NM_134011.3NP_598772.1  FAST kinase domain-containing protein 4 isoform 1

      See identical proteins and their annotated locations for NP_598772.1

      Status: VALIDATED

      Source sequence(s)
      AK144813, BB727683, BC031910, BY784127
      Consensus CDS
      CCDS24423.1
      UniProtKB/Swiss-Prot
      Q91YM4
      Related
      ENSMUSP00000000394.8, ENSMUST00000000394.14
      Conserved Domains (3) summary
      smart00952
      Location:562619
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:368437
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:453534
      FAST_2; FAST kinase-like protein, subdomain 2

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      6565598..6576089 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514607.5XP_006514670.1  FAST kinase domain-containing protein 4 isoform X1

      See identical proteins and their annotated locations for XP_006514670.1

      UniProtKB/Swiss-Prot
      Q91YM4
      Conserved Domains (3) summary
      smart00952
      Location:562619
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:368437
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:453534
      FAST_2; FAST kinase-like protein, subdomain 2
    2. XM_011243672.3XP_011241974.1  FAST kinase domain-containing protein 4 isoform X2

      Conserved Domains (3) summary
      smart00952
      Location:275332
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:81150
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:166247
      FAST_2; FAST kinase-like protein, subdomain 2

    RNA

    1. XR_001779944.2 RNA Sequence

      Related
      ENSMUST00000150697.8
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