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    Tbca tubulin cofactor A [ Mus musculus (house mouse) ]

    Gene ID: 21371, updated on 23-Jun-2021

    Summary

    Official Symbol
    Tbcaprovided by MGI
    Official Full Name
    tubulin cofactor Aprovided by MGI
    Primary source
    MGI:MGI:107549
    See related
    Ensembl:ENSMUSG00000042043
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tbca1; Tbca13
    Expression
    Biased expression in placenta adult (RPKM 123.1), CNS E18 (RPKM 104.1) and 14 other tissues See more
    Orthologs
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    Genomic context

    See Tbca in Genome Data Viewer
    Location:
    13; 13 C3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (94925428..94979431)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (94788920..94842923)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (95558898..95612854)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32351 Neighboring gene predicted gene, 46389 Neighboring gene orthopedia homeobox Neighboring gene predicted gene, 41024 Neighboring gene WD repeat domain 41

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables beta-tubulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables tubulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in post-chaperonin tubulin folding pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in tubulin complex assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in microtubule cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    tubulin-specific chaperone A
    Names
    CFA
    TCP1-chaperonin cofactor A
    co-chaperonin associated with a- & b-tubulin
    cofactor A
    tubulin-folding cofactor A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009321.3NP_033347.1  tubulin-specific chaperone A

      See identical proteins and their annotated locations for NP_033347.1

      Status: VALIDATED

      Source sequence(s)
      AK140276, BC051475
      Consensus CDS
      CCDS26694.1
      UniProtKB/Swiss-Prot
      P48428
      UniProtKB/TrEMBL
      Q5I0U7
      Related
      ENSMUSP00000038781.6, ENSMUST00000046644.7
      Conserved Domains (1) summary
      pfam02970
      Location:993
      TBCA; Tubulin binding cofactor A

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      94925428..94979431
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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