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    Arhgef11 Rho guanine nucleotide exchange factor (GEF) 11 [ Mus musculus (house mouse) ]

    Gene ID: 213498, updated on 23-Jun-2021

    Summary

    Official Symbol
    Arhgef11provided by MGI
    Official Full Name
    Rho guanine nucleotide exchange factor (GEF) 11provided by MGI
    Primary source
    MGI:MGI:2441869
    See related
    Ensembl:ENSMUSG00000041977
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P; Prg; RhoGEF; PDZ-Rho; mKIAA0380; PDZ-RhoGEF
    Expression
    Ubiquitous expression in ovary adult (RPKM 16.7), lung adult (RPKM 15.9) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Arhgef11 in Genome Data Viewer
    Location:
    3; 3 F1
    Exon count:
    43
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (87524855..87645346)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (87617548..87738039)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (87422673..87541955)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene ets variant 3-like Neighboring gene predicted gene, 25167 Neighboring gene ribosomal protein S27 pseudogene Neighboring gene predicted gene 6570 Neighboring gene leucine rich repeat containing 71 Neighboring gene platelet endothelial aggregation receptor 1 Neighboring gene neurotrophic tyrosine kinase, receptor, type 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • KIAA0380, MGC90827, B930073M02, E130307F09

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    rho guanine nucleotide exchange factor 11

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001003912.2NP_001003912.1  rho guanine nucleotide exchange factor 11 isoform 1

      See identical proteins and their annotated locations for NP_001003912.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC139241, AI836713, BC079565
      Consensus CDS
      CCDS38472.1
      UniProtKB/TrEMBL
      Q68FM7
      Related
      ENSMUSP00000039900.9, ENSMUST00000039476.15
      Conserved Domains (5) summary
      cd08753
      Location:330474
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      COG0265
      Location:61137
      DegQ; Periplasmic serine protease, S1-C subfamily, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]
      cd00992
      Location:46120
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9691111
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:768952
      RhoGEF; RhoGEF domain
    2. NM_001360195.1NP_001347124.1  rho guanine nucleotide exchange factor 11 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has multiple differences in the 5' coding region but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
      Source sequence(s)
      AC139241, AC161454, AI836713, BC079565
      Related
      ENSMUSP00000118123.2, ENSMUST00000129113.8
      Conserved Domains (5) summary
      cd08753
      Location:290434
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      smart00325
      Location:739923
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      cd00992
      Location:46120
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9401082
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      cl26464
      Location:10711413
      Atrophin-1; Atrophin-1 family
    3. NM_001360197.1NP_001347126.1  rho guanine nucleotide exchange factor 11 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate exon in the 5' region and uses a downstream start codon, compared to variant 1. The encoded isoform (3) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AC139241, AC161454, AI836713, BC072663
      Conserved Domains (3) summary
      PHA03247
      Location:450792
      PHA03247; large tegument protein UL36; Provisional
      cd13391
      Location:319461
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:118301
      RhoGEF; RhoGEF domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      87524855..87645346
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006501264.2XP_006501327.1  rho guanine nucleotide exchange factor 11 isoform X1

      Conserved Domains (5) summary
      cd08753
      Location:346490
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:11271469
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:62136
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9961138
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:795978
      RhoGEF; RhoGEF domain
    2. XM_006501272.2XP_006501335.1  rho guanine nucleotide exchange factor 11 isoform X13

      Conserved Domains (5) summary
      cd08753
      Location:346490
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03307
      Location:11691536
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00992
      Location:62136
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9961138
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:795978
      RhoGEF; RhoGEF domain
    3. XM_006501267.2XP_006501330.1  rho guanine nucleotide exchange factor 11 isoform X4

      Conserved Domains (5) summary
      cd08753
      Location:346490
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:11171459
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:62136
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9861128
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:785968
      RhoGEF; RhoGEF domain
    4. XM_006501265.2XP_006501328.1  rho guanine nucleotide exchange factor 11 isoform X2

      Conserved Domains (5) summary
      cd08753
      Location:346490
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:11261468
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:62136
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9951137
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:794977
      RhoGEF; RhoGEF domain
    5. XM_006501268.2XP_006501331.1  rho guanine nucleotide exchange factor 11 isoform X5

      Conserved Domains (5) summary
      cd08753
      Location:346490
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:11161458
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:62136
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9851127
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:784967
      RhoGEF; RhoGEF domain
    6. XM_036163000.1XP_036018893.1  rho guanine nucleotide exchange factor 11 isoform X18

      Conserved Domains (5) summary
      cd08753
      Location:346490
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      smart00325
      Location:784968
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      PHA03307
      Location:11581525
      PHA03307; transcriptional regulator ICP4; Provisional
      cd00992
      Location:62136
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9851127
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
    7. XM_006501273.2XP_006501336.1  rho guanine nucleotide exchange factor 11 isoform X14

      Conserved Domains (5) summary
      cd08753
      Location:300444
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:10811423
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:62136
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9501092
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:749932
      RhoGEF; RhoGEF domain
    8. XM_036163001.1XP_036018894.1  rho guanine nucleotide exchange factor 11 isoform X19

      Conserved Domains (5) summary
      cd08753
      Location:300444
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      smart00325
      Location:739923
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      PHA03247
      Location:10711413
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:62136
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9401082
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
    9. XM_006501270.2XP_006501333.1  rho guanine nucleotide exchange factor 11 isoform X11

      Conserved Domains (5) summary
      cd08753
      Location:306450
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:10871429
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:62136
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9561098
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:755938
      RhoGEF; RhoGEF domain
    10. XM_006501274.2XP_006501337.1  rho guanine nucleotide exchange factor 11 isoform X15

      Conserved Domains (5) summary
      cd08753
      Location:306450
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:10771419
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:62136
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9461088
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:745928
      RhoGEF; RhoGEF domain
    11. XM_006501271.2XP_006501334.1  rho guanine nucleotide exchange factor 11 isoform X12

      Conserved Domains (5) summary
      cd08753
      Location:306450
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:10861428
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:62136
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9551097
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:754937
      RhoGEF; RhoGEF domain
    12. XM_011240067.1XP_011238369.1  rho guanine nucleotide exchange factor 11 isoform X16

      Conserved Domains (5) summary
      cd08753
      Location:306450
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:10761418
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:62136
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9451087
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:744927
      RhoGEF; RhoGEF domain
    13. XM_006501266.2XP_006501329.1  rho guanine nucleotide exchange factor 11 isoform X3

      Conserved Domains (5) summary
      cd08753
      Location:341485
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:11221464
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:57131
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9911133
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:790973
      RhoGEF; RhoGEF domain
    14. XM_036162998.1XP_036018891.1  rho guanine nucleotide exchange factor 11 isoform X6

      Conserved Domains (5) summary
      cd08753
      Location:341485
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      smart00325
      Location:780964
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      PHA03247
      Location:11121454
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:57131
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9811123
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
    15. XM_030252534.1XP_030108394.1  rho guanine nucleotide exchange factor 11 isoform X8

      Conserved Domains (5) summary
      cd08753
      Location:341485
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:11111453
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:57131
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9801122
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:779962
      RhoGEF; RhoGEF domain
    16. XM_030252536.1XP_030108396.1  rho guanine nucleotide exchange factor 11 isoform X17

      Conserved Domains (5) summary
      cd08753
      Location:295439
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:10761418
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:57131
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9451087
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:744927
      RhoGEF; RhoGEF domain
    17. XM_006501269.2XP_006501332.1  rho guanine nucleotide exchange factor 11 isoform X7

      Conserved Domains (5) summary
      cd08753
      Location:330474
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:11111453
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:46120
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9801122
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:779962
      RhoGEF; RhoGEF domain
    18. XM_036162999.1XP_036018892.1  rho guanine nucleotide exchange factor 11 isoform X10

      Conserved Domains (5) summary
      cd08753
      Location:330474
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      smart00325
      Location:769953
      RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases
      PHA03247
      Location:11011443
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:46120
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9701112
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
    19. XM_030252535.1XP_030108395.1  rho guanine nucleotide exchange factor 11 isoform X9

      Conserved Domains (5) summary
      cd08753
      Location:330474
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:11101452
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:46120
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9791121
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:778961
      RhoGEF; RhoGEF domain
    20. XM_030252537.1XP_030108397.1  rho guanine nucleotide exchange factor 11 isoform X20

      Conserved Domains (5) summary
      cd08753
      Location:284428
      RGS_PDZRhoGEF; Regulator of G protein signaling (RGS) domain found in the PDZ-Rho guanine nucleotide exchange factor (RhoGEF) protein
      PHA03247
      Location:10651407
      PHA03247; large tegument protein UL36; Provisional
      cd00992
      Location:46120
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd13391
      Location:9341076
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:733916
      RhoGEF; RhoGEF domain
    21. XM_030252538.1XP_030108398.1  rho guanine nucleotide exchange factor 11 isoform X21

      Conserved Domains (3) summary
      PHA03247
      Location:450792
      PHA03247; large tegument protein UL36; Provisional
      cd13391
      Location:319461
      PH_PRG; PDZ Rho guanine nucleotide exchange factor Pleckstrin homology (PH) domain
      pfam00621
      Location:118301
      RhoGEF; RhoGEF domain

    RNA

    1. XR_004941301.1 RNA Sequence

      Related
      ENSMUST00000152006.2
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