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    Scyl2 SCY1-like 2 (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 213326, updated on 23-Jun-2021

    Summary

    Official Symbol
    Scyl2provided by MGI
    Official Full Name
    SCY1-like 2 (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1289172
    See related
    Ensembl:ENSMUSG00000069539
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CVAK1; CVAK104; AU015688; AW536445; BC030932; D10Ertd802; D10Ertd802e
    Expression
    Ubiquitous expression in CNS E18 (RPKM 10.5), CNS E14 (RPKM 10.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Scyl2 in Genome Data Viewer
    Location:
    10 C2; 10 45.05 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (89474582..89522179, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (89638720..89686317, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (89102852..89149030, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene nuclear receptor subfamily 1, group H, member 4 Neighboring gene solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 Neighboring gene RIKEN cDNA 1500026H17 gene Neighboring gene ARP6 actin-related protein 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    SCY1-like protein 2
    Names
    coated vesicle-associated kinase of 104 kDa

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310704.2NP_001297633.1  SCY1-like protein 2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC127279, AI661906
      Consensus CDS
      CCDS78881.1
      UniProtKB/TrEMBL
      G5E8J9
      Related
      ENSMUSP00000089874.6, ENSMUST00000092227.12
      Conserved Domains (4) summary
      smart00220
      Location:32327
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08430
      Location:741873
      Forkhead_N; Forkhead N-terminal region
      cd14011
      Location:38329
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:373403
      HEAT; HEAT repeat [structural motif]
    2. NM_001358843.1NP_001345772.1  SCY1-like protein 2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC127279, AI661906, CB247519, CN528758
      Conserved Domains (3) summary
      cd14011
      Location:38329
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:373403
      HEAT; HEAT repeat [structural motif]
      pfam08430
      Location:745883
      Forkhead_N; Forkhead N-terminal region
    3. NM_198021.3NP_932138.1  SCY1-like protein 2 isoform 1

      See identical proteins and their annotated locations for NP_932138.1

      Status: VALIDATED

      Source sequence(s)
      AC127279, AI661906
      Consensus CDS
      CCDS36027.1
      UniProtKB/Swiss-Prot
      Q8CFE4
      Related
      ENSMUSP00000133992.2, ENSMUST00000174252.8
      Conserved Domains (4) summary
      smart00220
      Location:32327
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      pfam08430
      Location:742874
      Forkhead_N; Forkhead N-terminal region
      cd14011
      Location:38329
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:373403
      HEAT; HEAT repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      89474582..89522179 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011243394.3XP_011241696.1  SCY1-like protein 2 isoform X1

      Conserved Domains (3) summary
      cd14011
      Location:38329
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
      sd00044
      Location:373403
      HEAT; HEAT repeat [structural motif]
      pfam08430
      Location:746884
      Forkhead_N; Forkhead N-terminal region
    2. XM_036155724.1XP_036011617.1  SCY1-like protein 2 isoform X2

      Conserved Domains (1) summary
      cd14011
      Location:38329
      PK_SCY1_like; Pseudokinase domain of Scy1-like proteins
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