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    Rnf26 ring finger protein 26 [ Mus musculus (house mouse) ]

    Gene ID: 213211, updated on 18-Sep-2024

    Summary

    Official Symbol
    Rnf26provided by MGI
    Official Full Name
    ring finger protein 26provided by MGI
    Primary source
    MGI:MGI:2388131
    See related
    Ensembl:ENSMUSG00000053128 AllianceGenome:MGI:2388131
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    8030450I18Rik
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in several processes, including cellular protein metabolic process; negative regulation of defense response to virus; and protein localization to perinuclear region of cytoplasm. Predicted to be located in endoplasmic reticulum membrane. Is expressed in female associated reproductive structure and urinary system. Orthologous to human RNF26 (ring finger protein 26). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See Rnf26 in Genome Data Viewer
    Location:
    9 A5.1; 9 24.53 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (44022078..44024348, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (44110781..44113051, complement)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 2 Neighboring gene predicted gene, 38444 Neighboring gene C1q and tumor necrosis factor related protein 5 Neighboring gene membrane frizzled-related protein Neighboring gene STARR-seq mESC enhancer starr_23954 Neighboring gene STARR-seq mESC enhancer starr_23955 Neighboring gene predicted gene 10687 Neighboring gene STARR-seq mESC enhancer starr_23959 Neighboring gene melanoma cell adhesion molecule

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin protein ligase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in endosome organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endosome organization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of defense response to virus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of defense response to virus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein K11-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein K11-linked ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein localization to perinuclear region of cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein localization to perinuclear region of cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of type I interferon production ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of type I interferon production ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase RNF26
    NP_717095.2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153762.3NP_717095.2  E3 ubiquitin-protein ligase RNF26

      See identical proteins and their annotated locations for NP_717095.2

      Status: PROVISIONAL

      Source sequence(s)
      BC063251
      Consensus CDS
      CCDS23096.1
      UniProtKB/Swiss-Prot
      F6SS41, Q5PR90, Q8BUH7, Q8BZY8, Q99KC1
      UniProtKB/TrEMBL
      E9PVG0
      Related
      ENSMUSP00000110478.3, ENSMUST00000056328.6
      Conserved Domains (1) summary
      pfam13920
      Location:367419
      zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      44022078..44024348 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)