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    Fam126b family with sequence similarity 126, member B [ Mus musculus (house mouse) ]

    Gene ID: 213056, updated on 2-Oct-2018

    Summary

    Official Symbol
    Fam126bprovided by MGI
    Official Full Name
    family with sequence similarity 126, member Bprovided by MGI
    Primary source
    MGI:MGI:1098784
    See related
    Ensembl:ENSMUSG00000038174 Vega:OTTMUSG00000026622
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D1Ertd53e; D630010C10; C130065N10Rik
    Expression
    Broad expression in cortex adult (RPKM 5.3), cerebellum adult (RPKM 5.2) and 22 other tissues See more
    Orthologs

    Genomic context

    See Fam126b in Genome Data Viewer
    Location:
    1 C1.3; 1 29.12 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 1 NC_000067.6 (58522806..58586333, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (58579650..58643177, complement)

    Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene peptidylprolyl isomerase (cyclophilin)-like 3 Neighboring gene Ngg1 interacting factor 3-like 1 (S. pombe) Neighboring gene origin recognition complex, subunit 2 Neighboring gene predicted gene 15834 Neighboring gene NADH:ubiquinone oxidoreductase subunit B3 Neighboring gene predicted gene 29389

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    phosphatidylinositol phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein localization to plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    intracellular ISO
    Inferred from Sequence Orthology
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001310598.1NP_001297527.1  protein FAM126B isoform a

      See identical proteins and their annotated locations for NP_001297527.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC118698, AK168372, CA556879
      Consensus CDS
      CCDS78588.1
      UniProtKB/Swiss-Prot
      Q8C729
      Related
      ENSMUSP00000095331.3, OTTMUSP00000032890, ENSMUST00000097724.9, OTTMUST00000065878
      Conserved Domains (1) summary
      pfam09790
      Location:22330
      Hyccin; Hyccin
    2. NM_001310599.1NP_001297528.1  protein FAM126B isoform b

      See identical proteins and their annotated locations for NP_001297528.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
      Source sequence(s)
      AC118698, AK052638, BY265998
      Consensus CDS
      CCDS14976.1
      UniProtKB/Swiss-Prot
      Q8C729
      Related
      ENSMUSP00000038718.7, OTTMUSP00000032891, ENSMUST00000038372.13, OTTMUST00000065879
      Conserved Domains (1) summary
      pfam09790
      Location:22330
      Hyccin; Hyccin
    3. NM_172513.3NP_766101.3  protein FAM126B isoform b

      See identical proteins and their annotated locations for NP_766101.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Variants 2 and 3 both encode the same isoform (b).
      Source sequence(s)
      AC118698
      Consensus CDS
      CCDS14976.1
      UniProtKB/Swiss-Prot
      Q8C729
      Related
      ENSMUSP00000123728.1, OTTMUSP00000032889, ENSMUST00000161600.7, OTTMUST00000065877
      Conserved Domains (1) summary
      pfam09790
      Location:22330
      Hyccin; Hyccin

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000067.6 Reference GRCm38.p4 C57BL/6J

      Range
      58522806..58586333 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006495833.2XP_006495896.1  protein FAM126B isoform X1

      See identical proteins and their annotated locations for XP_006495896.1

      UniProtKB/Swiss-Prot
      Q8C729
      Conserved Domains (1) summary
      pfam09790
      Location:22330
      Hyccin; Hyccin
    2. XM_017319658.1XP_017175147.1  protein FAM126B isoform X3

    3. XM_017319657.1XP_017175146.1  protein FAM126B isoform X2

      UniProtKB/Swiss-Prot
      Q8C729
      Conserved Domains (1) summary
      pfam09790
      Location:22330
      Hyccin; Hyccin
    4. XM_006495832.2XP_006495895.1  protein FAM126B isoform X1

      See identical proteins and their annotated locations for XP_006495895.1

      UniProtKB/Swiss-Prot
      Q8C729
      Conserved Domains (1) summary
      pfam09790
      Location:22330
      Hyccin; Hyccin
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