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    Mms22l MMS22-like, DNA repair protein [ Mus musculus (house mouse) ]

    Gene ID: 212377, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mms22lprovided by MGI
    Official Full Name
    MMS22-like, DNA repair proteinprovided by MGI
    Primary source
    MGI:MGI:2684980
    See related
    Ensembl:ENSMUSG00000045751
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm134; F730047E07Rik
    Expression
    Broad expression in liver E14.5 (RPKM 6.1), CNS E11.5 (RPKM 6.0) and 21 other tissues See more
    Orthologs
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    Genomic context

    See Mms22l in Genome Data Viewer
    Location:
    4; 4 A3
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (24496451..24602950)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (24496451..24602950)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (24423609..24530097)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 31145 Neighboring gene predicted gene 27243 Neighboring gene tubulin, beta 5 pseudogene Neighboring gene kelch-like 32 Neighboring gene predicted gene, 31436 Neighboring gene predicted gene, 31379

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cellular response to DNA damage stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in double-strand break repair via homologous recombination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in replication fork processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in replication fork processing ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of FACT complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of MCM complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nuclear replication fork IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nuclear replication fork ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199467.3NP_955761.2  protein MMS22-like

      See identical proteins and their annotated locations for NP_955761.2

      Status: VALIDATED

      Source sequence(s)
      AK089531, AK164069, BC094429, BX296536, CK639437
      Consensus CDS
      CCDS18006.2
      UniProtKB/Swiss-Prot
      B1AUR6
      Related
      ENSMUSP00000103857.3, ENSMUST00000108222.9
      Conserved Domains (2) summary
      pfam14910
      Location:26730
      MMS22L_N; S-phase genomic integrity recombination mediator, N-terminal
      pfam14911
      Location:8491225
      MMS22L_C; S-phase genomic integrity recombination mediator, C-terminal

    RNA

    1. NR_149739.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AK089531, AK164069, AL671913, BC094429, BE623427, BX296536, CK639437

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      24496451..24602950
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006537730.4XP_006537793.1  protein MMS22-like isoform X1

      See identical proteins and their annotated locations for XP_006537793.1

      Conserved Domains (2) summary
      pfam14910
      Location:26730
      MMS22L_N; S-phase genomic integrity recombination mediator, N-terminal
      pfam14911
      Location:8501226
      MMS22L_C; S-phase genomic integrity recombination mediator, C-terminal
    2. XM_036163937.1XP_036019830.1  protein MMS22-like isoform X1

      Conserved Domains (2) summary
      pfam14910
      Location:26730
      MMS22L_N; S-phase genomic integrity recombination mediator, N-terminal
      pfam14911
      Location:8501226
      MMS22L_C; S-phase genomic integrity recombination mediator, C-terminal
    3. XM_036163938.1XP_036019831.1  protein MMS22-like isoform X2

      Conserved Domains (2) summary
      pfam14910
      Location:26730
      MMS22L_N; S-phase genomic integrity recombination mediator, N-terminal
      pfam14911
      Location:8491225
      MMS22L_C; S-phase genomic integrity recombination mediator, C-terminal
    4. XM_036163939.1XP_036019832.1  protein MMS22-like isoform X3

      Conserved Domains (2) summary
      pfam14910
      Location:11369
      MMS22L_N; S-phase genomic integrity recombination mediator, N-terminal
      pfam14911
      Location:489865
      MMS22L_C; S-phase genomic integrity recombination mediator, C-terminal
    5. XM_011249970.4XP_011248272.1  protein MMS22-like isoform X4

      Conserved Domains (2) summary
      pfam14910
      Location:29249
      MMS22L_N; S-phase genomic integrity recombination mediator, N-terminal
      pfam14911
      Location:369745
      MMS22L_C; S-phase genomic integrity recombination mediator, C-terminal

    RNA

    1. XR_003954900.1 RNA Sequence

    2. XR_003954899.1 RNA Sequence

    3. XR_004941857.1 RNA Sequence

      Related
      ENSMUST00000154349.9
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