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    Cc2d1a coiled-coil and C2 domain containing 1A [ Mus musculus (house mouse) ]

    Gene ID: 212139, updated on 31-Jan-2019

    Summary

    Official Symbol
    Cc2d1aprovided by MGI
    Official Full Name
    coiled-coil and C2 domain containing 1Aprovided by MGI
    Primary source
    MGI:MGI:2384831
    See related
    Ensembl:ENSMUSG00000036686
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tape; Freud-1; BC016188
    Expression
    Ubiquitous expression in colon adult (RPKM 20.2), CNS E18 (RPKM 19.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cc2d1a in Genome Data Viewer
    Location:
    8; 8 C2
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 8 NC_000074.6 (84132828..84147931, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (86656727..86671652, complement)

    Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene regulatory factor X, 1 (influences HLA class II expression) Neighboring gene microRNA 709 Neighboring gene DDB1 and CUL4 associated factor 15 Neighboring gene predicted gene, 39210 Neighboring gene podocan-like 1 Neighboring gene RIKEN cDNA 4930432K21 gene Neighboring gene nanos C2HC-type zinc finger 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    • SIDS Susceptibility Pathways, organism-specific biosystem (from WikiPathways)
      SIDS Susceptibility Pathways, organism-specific biosystemIn this model, we provide an integrated view of Sudden Infant Death Syndrome (SIDS) at the level of implicated tissues, signaling networks and genetics. The purpose of this model is to serve as an ov...

    General gene information

    Homology

    Clone Names

    • MGC27560, MGC38983

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    negative regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    fibrillar center ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    coiled-coil and C2 domain-containing protein 1A
    Names
    5-HT1A receptor
    FRE under dual repression-binding protein 1
    five prime repressor element under dual repression-binding protein 1
    five' repressor element under dual repression binding protein 1
    putative NFkB activating protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145970.2NP_666082.2  coiled-coil and C2 domain-containing protein 1A

      See identical proteins and their annotated locations for NP_666082.2

      Status: VALIDATED

      Source sequence(s)
      AC159266
      Consensus CDS
      CCDS40407.1
      UniProtKB/Swiss-Prot
      Q8K1A6
      Related
      ENSMUSP00000046449.8, ENSMUST00000040383.8
      Conserved Domains (3) summary
      smart00685
      Location:342400
      DM14; Repeats in fly CG4713, worm Y37H9A.3 and human FLJ20241
      cd08690
      Location:645802
      C2_Freud-1; C2 domain found in 5' repressor element under dual repression binding protein-1 (Freud-1)
      pfam07404
      Location:442496
      TEBP_beta; Telomere-binding protein beta subunit (TEBP beta)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000074.6 Reference GRCm38.p4 C57BL/6J

      Range
      84132828..84147931 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530810.2XP_006530873.1  coiled-coil and C2 domain-containing protein 1A isoform X1

      Related
      ENSMUSP00000112556.2, ENSMUST00000117424.8
      Conserved Domains (2) summary
      smart00685
      Location:342400
      DM14; Repeats in fly CG4713, worm Y37H9A.3 and human FLJ20241
      cd08690
      Location:644801
      C2_Freud-1; C2 domain found in 5' repressor element under dual repression binding protein-1 (Freud-1)
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