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    Pank3 pantothenate kinase 3 [ Mus musculus (house mouse) ]

    Gene ID: 211347, updated on 23-Jun-2021

    Summary

    Official Symbol
    Pank3provided by MGI
    Official Full Name
    pantothenate kinase 3provided by MGI
    Primary source
    MGI:MGI:2387464
    See related
    Ensembl:ENSMUSG00000018846
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in subcutaneous fat pad adult (RPKM 15.7), genital fat pad adult (RPKM 13.8) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Pank3 in Genome Data Viewer
    Location:
    11; 11 A4
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (35660322..35682112)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (35769495..35791285)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (35582997..35604787)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene slit guidance ligand 3 Neighboring gene microRNA 218-2 Neighboring gene predicted gene, 46278 Neighboring gene microRNA 103-1 Neighboring gene fibrillarin-like 1 Neighboring gene arginyl-tRNA synthetase

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Clone Names

    • MGC38148

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables acetyl-CoA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables pantothenate kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables pantothenate kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables pantothenate kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables pantothenate kinase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein homodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables vitamin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in coenzyme A biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within coenzyme A biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in coenzyme A biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in phosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    pantothenate kinase 3
    Names
    mPanK3
    pantothenic acid kinase 3
    NP_666074.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145962.2NP_666074.1  pantothenate kinase 3

      See identical proteins and their annotated locations for NP_666074.1

      Status: VALIDATED

      Source sequence(s)
      AK039865, AL596084, CD541217, CJ127650
      Consensus CDS
      CCDS24543.1
      UniProtKB/Swiss-Prot
      Q8R2W9
      UniProtKB/TrEMBL
      Q5SXA7
      Related
      ENSMUSP00000018990.8, ENSMUST00000018990.8
      Conserved Domains (1) summary
      pfam03630
      Location:14362
      Fumble

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      35660322..35682112
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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