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    Ints9 integrator complex subunit 9 [ Mus musculus (house mouse) ]

    Gene ID: 210925, updated on 5-Aug-2018

    Summary

    Official Symbol
    Ints9provided by MGI
    Official Full Name
    integrator complex subunit 9provided by MGI
    Primary source
    MGI:MGI:1098533
    See related
    Ensembl:ENSMUSG00000021975
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BC028953; D14Ertd231e
    Expression
    Ubiquitous expression in thymus adult (RPKM 12.8), limb E14.5 (RPKM 10.8) and 28 other tissues See more
    Orthologs

    Genomic context

    See Ints9 in Genome Data Viewer
    Location:
    14 D1; 14 33.81 cM
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 14 NC_000080.6 (64950045..65039835)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 14 NC_000080.5 (65568882..65658663)

    Chromosome 14 - NC_000080.6Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L35a pseudogene Neighboring gene homeobox containing 1 Neighboring gene high mobility group nucleosomal binding domain 2, pseudogene Neighboring gene exostoses (multiple)-like 3 Neighboring gene predicted gene, 30008 Neighboring gene predicted gene, 41177

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    snRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    integrator complex ISO
    Inferred from Sequence Orthology
    more info
     
    nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    integrator complex subunit 9
    Names
    int9

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001253731.1NP_001240660.1  integrator complex subunit 9 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an alternate splice site in the 5' region, which results in a downstream AUG start codon, compared to variant 1. The resulting isoform (2) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AK077634, BQ033503, BY195822
      UniProtKB/Swiss-Prot
      Q8K114
      Conserved Domains (2) summary
      smart01027
      Location:283401
      Beta-Casp; Beta-Casp domain
      cl23716
      Location:60241
      metallo-hydrolase-like_MBL-fold; mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain
    2. NM_153414.4NP_700463.2  integrator complex subunit 9 isoform 1

      See identical proteins and their annotated locations for NP_700463.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK077634, BQ033503
      Consensus CDS
      CCDS27210.1
      UniProtKB/Swiss-Prot
      Q8K114
      UniProtKB/TrEMBL
      A0A0R4J0J5
      Related
      ENSMUSP00000045552.5, ENSMUST00000043914.6
      Conserved Domains (2) summary
      smart01027
      Location:336454
      Beta-Casp; Beta-Casp domain
      cd16294
      Location:30294
      Int9-like_MBL-fold; integrator subunit 9, and related proteins; MBL-fold metallo-hydrolase domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000080.6 Reference GRCm38.p4 C57BL/6J

      Range
      64950045..65039835
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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