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    Nemp1 nuclear envelope integral membrane protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 210035, updated on 5-Aug-2018

    Summary

    Official Symbol
    Nemp1provided by MGI
    Official Full Name
    nuclear envelope integral membrane protein 1provided by MGI
    Primary source
    MGI:MGI:2446113
    See related
    Ensembl:ENSMUSG00000040195 Vega:OTTMUSG00000031893
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tmem194; Tmem194a
    Expression
    Biased expression in testis adult (RPKM 9.0), liver E14 (RPKM 1.3) and 12 other tissues See more
    Orthologs

    Genomic context

    See Nemp1 in Genome Data Viewer
    Location:
    10; 10 D3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (127677065..127701049)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (127114121..127138103)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene signal transducer and activator of transcription 6 Neighboring gene RIKEN cDNA 1700012D01 gene Neighboring gene Ngfi-A binding protein 2 Neighboring gene predicted gene 16230 Neighboring gene myosin IA Neighboring gene tachykinin 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC40914

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nuclear envelope IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nuclear envelope IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    nuclear envelope integral membrane protein 1
    Names
    transmembrane protein 194
    transmembrane protein 194A

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001113211.1NP_001106682.1  nuclear envelope integral membrane protein 1 isoform 1 precursor

      See identical proteins and their annotated locations for NP_001106682.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer protein (isoform 1).
      Source sequence(s)
      AC160970, AK129110
      Consensus CDS
      CCDS48720.1
      UniProtKB/Swiss-Prot
      Q6ZQE4
      Related
      ENSMUSP00000045988.4, OTTMUSP00000042133, ENSMUST00000048099.4, OTTMUST00000079064
      Conserved Domains (1) summary
      pfam10225
      Location:150396
      DUF2215; Uncharacterized conserved protein (DUF2215)
    2. NM_173732.3NP_776093.1  nuclear envelope integral membrane protein 1 isoform 2 precursor

      See identical proteins and their annotated locations for NP_776093.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses a different segment for its 3' coding region and 3' UTR, compared to variant 1. The resulting protein (isoform 2) has a distinct and shorter C-terminus when it is compared to isoform 1.
      Source sequence(s)
      AC160970, AK090031
      Consensus CDS
      CCDS48721.1
      UniProtKB/TrEMBL
      Q8K2N3
      Related
      ENSMUSP00000113337.1, OTTMUSP00000042135, ENSMUST00000118612.7, OTTMUST00000079067
      Conserved Domains (1) summary
      pfam10225
      Location:150321
      DUF2215; Uncharacterized conserved protein (DUF2215)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      127677065..127701049
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011243393.1XP_011241695.1  nuclear envelope integral membrane protein 1 isoform X1

      Conserved Domains (1) summary
      pfam10225
      Location:1207
      DUF2215; Uncharacterized conserved protein (DUF2215)
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