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    Nudcd3 NudC domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 209586, updated on 23-Jun-2021

    Summary

    Official Symbol
    Nudcd3provided by MGI
    Official Full Name
    NudC domain containing 3provided by MGI
    Primary source
    MGI:MGI:2144158
    See related
    Ensembl:ENSMUSG00000053838
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    AI427847; BC024322; mKIAA1068
    Expression
    Ubiquitous expression in cortex adult (RPKM 21.3), frontal lobe adult (RPKM 20.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Nudcd3 in Genome Data Viewer
    Location:
    11; 11 A1
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (6055691..6151619, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (6105691..6201619, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (6005694..6100454, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene YKT6 v-SNARE homolog (S. cerevisiae) Neighboring gene calcium/calmodulin-dependent protein kinase II, beta Neighboring gene ribosomal protein S15A, pseudogene 6 Neighboring gene NPC1 like intracellular cholesterol transporter 1 Neighboring gene predicted gene 11401

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA1068

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables unfolded protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cilium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in protein folding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein localization to pericentriolar material ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of cytoplasmic dynein complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    nudC domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363446.1NP_001350375.1  nudC domain-containing protein 3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK050476, AL607152, AL611926
      Conserved Domains (2) summary
      pfam14050
      Location:967
      Nudc_N; N-terminal conserved domain of Nudc
      cl00175
      Location:186239
      alpha-crystallin-Hsps_p23-like; alpha-crystallin domain (ACD) found in alpha-crystallin-type small heat shock proteins, and a similar domain found in p23 (a cochaperone for Hsp90) and in other p23-like proteins.
    2. NM_173748.5NP_776109.1  nudC domain-containing protein 3 isoform 1

      See identical proteins and their annotated locations for NP_776109.1

      Status: VALIDATED

      Source sequence(s)
      AK049739, AW048333, BY085752, CF738060
      Consensus CDS
      CCDS24412.1
      UniProtKB/Swiss-Prot
      Q8R1N4
      UniProtKB/TrEMBL
      B0FTY3
      Related
      ENSMUSP00000064668.4, ENSMUST00000066496.10
      Conserved Domains (2) summary
      cd06495
      Location:186287
      p23_NUDCD3_like; p23-like NUD (nuclear distribution) C-like domain found in human NUDC domain-containing protein 3 (NUDCD3) and similar proteins. Little is known about the function of the proteins in this subgroup.
      pfam14050
      Location:967
      Nudc_N; N-terminal conserved domain of Nudc

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      6055691..6151619 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001779940.3 RNA Sequence

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