Format

Send to:

Choose Destination
    • Showing Current items.

    Supt4a SPT4A, DSIF elongation factor subunit [ Mus musculus (house mouse) ]

    Gene ID: 20922, updated on 23-Jun-2021

    Summary

    Official Symbol
    Supt4aprovided by MGI
    Official Full Name
    SPT4A, DSIF elongation factor subunitprovided by MGI
    Primary source
    MGI:MGI:107416
    See related
    Ensembl:ENSMUSG00000020485
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Supt; Supt4; Supt4h; Supt4h1; AL022777; Supt4h1a
    Expression
    Ubiquitous expression in liver E14 (RPKM 38.8), liver E14.5 (RPKM 36.0) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Supt4a in Genome Data Viewer
    Location:
    11 C; 11 52.2 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (87628377..87634449)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (87737551..87743623)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (87551067..87557119)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene ring finger protein 43 Neighboring gene RIKEN cDNA 1110028F11 gene Neighboring gene predicted gene, 25968 Neighboring gene microRNA 142b Neighboring gene TSPO associated protein 1 Neighboring gene microRNA 142

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA polymerase II complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein heterodimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of DSIF complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of DSIF complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    transcription elongation factor SPT4-A
    Names
    DRB sensitivity-inducing factor small subunit 1
    DSIF small subunit 1
    Transcription elongation factor SPT4-A
    suppressor of Ty 4 homolog 1
    suppressor of Ty 4A
    transcription elongation factor SPT4 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001355753.1NP_001342682.1  transcription elongation factor SPT4-A isoform 2

      Status: VALIDATED

      Source sequence(s)
      AK002990, AL604022, BQ176059, W47755
      Conserved Domains (1) summary
      cd07973
      Location:4290
      Spt4; Transcription elongation factor Spt4
    2. NM_009296.2NP_033322.1  transcription elongation factor SPT4-A isoform 1

      See identical proteins and their annotated locations for NP_033322.1

      Status: VALIDATED

      Source sequence(s)
      BQ176059, DV044501, DV061290
      Consensus CDS
      CCDS36270.1
      UniProtKB/Swiss-Prot
      P63271
      Related
      ENSMUSP00000091487.6, ENSMUST00000093955.12
      Conserved Domains (1) summary
      cd07973
      Location:11108
      Spt4; Transcription elongation factor Spt4

    RNA

    1. NR_149756.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK002990, AL604022, BQ176059, DV061290, W47755
      Related
      ENSMUST00000152700.8
    2. NR_149757.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK002990, AL604022, BQ176059, DV061290
      Related
      ENSMUST00000141169.2

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      87628377..87634449
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center