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    Eif1 eukaryotic translation initiation factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 20918, updated on 23-Jun-2021

    Summary

    Official Symbol
    Eif1provided by MGI
    Official Full Name
    eukaryotic translation initiation factor 1provided by MGI
    Primary source
    MGI:MGI:105125
    See related
    Ensembl:ENSMUSG00000035530
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sui1; Sui1-rs1
    Expression
    Ubiquitous expression in bladder adult (RPKM 117.5), liver E14 (RPKM 95.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Eif1 in Genome Data Viewer
    Location:
    11; 11 D
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (100210775..100212925)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (100319949..100322099)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (100181308..100183410)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene keratin 42 Neighboring gene predicted gene 14206 Neighboring gene gastrin Neighboring gene huntingtin-associated protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC6503, MGC101938

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ribosomal small subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within dosage compensation by inactivation of X chromosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of translational initiation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    part_of eukaryotic 43S preinitiation complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 1
    Names
    protein translation factor SUI1 homolog
    suppressor of initiator codon mutations, related sequence 1
    suppressor of initiator codon mutations-Yeast homolog related sequence 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011508.2NP_035638.1  eukaryotic translation initiation factor 1

      See identical proteins and their annotated locations for NP_035638.1

      Status: VALIDATED

      Source sequence(s)
      AK151070, AL590968, CD773876
      Consensus CDS
      CCDS25417.1
      UniProtKB/Swiss-Prot
      P48024
      UniProtKB/TrEMBL
      Q4V9T8
      Related
      ENSMUSP00000041538.8, ENSMUST00000049385.14
      Conserved Domains (1) summary
      cl00229
      Location:3113
      eIF1_SUI1_like; Eukaryotic initiation factor 1 and related proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      100210775..100212925
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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