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    Eif1 eukaryotic translation initiation factor 1 [ Mus musculus (house mouse) ]

    Gene ID: 20918, updated on 31-Jan-2019

    Summary

    Official Symbol
    Eif1provided by MGI
    Official Full Name
    eukaryotic translation initiation factor 1provided by MGI
    Primary source
    MGI:MGI:105125
    See related
    Ensembl:ENSMUSG00000035530
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sui1-rs1
    Expression
    Ubiquitous expression in bladder adult (RPKM 117.5), liver E14 (RPKM 95.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Eif1 in Genome Data Viewer
    Location:
    11; 11 D
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 11 NC_000077.6 (100319949..100322099)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (100181308..100183410)

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene keratin 42 Neighboring gene predicted gene 14206 Neighboring gene gastrin Neighboring gene huntingtin-associated protein 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    • RNA transport, organism-specific biosystem (from KEGG)
      RNA transport, organism-specific biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
    • RNA transport, conserved biosystem (from KEGG)
      RNA transport, conserved biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
    • Translation Factors, organism-specific biosystem (from WikiPathways)
      Translation Factors, organism-specific biosystem
      Translation Factors

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC6503, MGC101938

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ribosomal small subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    translation initiation factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    dosage compensation by inactivation of X chromosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    translation IEA
    Inferred from Electronic Annotation
    more info
     
    translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    eukaryotic 43S preinitiation complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    eukaryotic translation initiation factor 1
    Names
    protein translation factor SUI1 homolog
    suppressor of initiator codon mutations, related sequence 1
    suppressor of initiator codon mutations-Yeast homolog related sequence 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011508.2NP_035638.1  eukaryotic translation initiation factor 1

      See identical proteins and their annotated locations for NP_035638.1

      Status: VALIDATED

      Source sequence(s)
      AK151070, AL590968, CD773876
      Consensus CDS
      CCDS25417.1
      UniProtKB/Swiss-Prot
      P48024
      UniProtKB/TrEMBL
      Q4V9T8
      Related
      ENSMUSP00000041538.7, ENSMUST00000049385.13
      Conserved Domains (1) summary
      cl00229
      Location:3113
      eIF1_SUI1_like; Eukaryotic initiation factor 1 and related proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p4 C57BL/6J

      Range
      100319949..100322099
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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