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    Daam1 dishevelled associated activator of morphogenesis 1 [ Mus musculus (house mouse) ]

    Gene ID: 208846, updated on 25-Sep-2018

    Summary

    Official Symbol
    Daam1provided by MGI
    Official Full Name
    dishevelled associated activator of morphogenesis 1provided by MGI
    Primary source
    MGI:MGI:1914596
    See related
    Ensembl:ENSMUSG00000034574
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Ubiquitous expression in CNS E18 (RPKM 12.5), whole brain E14.5 (RPKM 8.6) and 25 other tissues See more
    Orthologs

    Genomic context

    See Daam1 in Genome Data Viewer
    Location:
    12; 12 C3
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 12 NC_000078.6 (71831047..71992376)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (72932065..73093354)

    Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 9630002D21 gene Neighboring gene predicted gene, 40439 Neighboring gene predicted gene, 46356 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene predicted gene, 40887 Neighboring gene predicted gene, 40440 Neighboring gene predicted gene 7986

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • mKIAA0666, E130308H01, 1700066F09Rik, 2310028E21Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    Rho GTPase binding IEA
    Inferred from Electronic Annotation
    more info
     
    actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    Wnt signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    actin cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
     
    cellular component organization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    ciliary basal body ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    motile cilium ISO
    Inferred from Sequence Orthology
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    stress fiber IDA
    Inferred from Direct Assay
    more info
    PubMed 
    stress fiber ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    disheveled-associated activator of morphogenesis 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001286452.1NP_001273381.1  disheveled-associated activator of morphogenesis 1 isoform b

      See identical proteins and their annotated locations for NP_001273381.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and lacks an in-frame exon in the central coding region, compared to variant 1. The encoded isoform (b) is shorter, compared to isoform a.
      Source sequence(s)
      AC159186, AK033683, AK147480, AK162231, BC076585
      UniProtKB/Swiss-Prot
      Q8BPM0
      UniProtKB/TrEMBL
      Q8BTF1
      Related
      ENSMUSP00000152532.1, ENSMUST00000221317.1
      Conserved Domains (4) summary
      pfam02181
      Location:600973
      FH2; Formin Homology 2 Domain
      pfam06367
      Location:235439
      Drf_FH3; Diaphanous FH3 Domain
      pfam06371
      Location:45232
      Drf_GBD; Diaphanous GTPase-binding Domain
      pfam10211
      Location:450507
      Ax_dynein_light; Axonemal dynein light chain
    2. NM_026102.3NP_080378.2  disheveled-associated activator of morphogenesis 1 isoform a

      See identical proteins and their annotated locations for NP_080378.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (a). Both variants 1 and 2 encode the same isoform.
      Source sequence(s)
      AC124356, AK033683, AK162231, BC076585, CD352113
      Consensus CDS
      CCDS25964.1
      UniProtKB/Swiss-Prot
      Q8BPM0
      UniProtKB/TrEMBL
      Q8BTF1
      Related
      ENSMUSP00000082406.2, ENSMUST00000085299.3
      Conserved Domains (4) summary
      pfam02181
      Location:600982
      FH2; Formin Homology 2 Domain
      pfam06367
      Location:235439
      Drf_FH3; Diaphanous FH3 Domain
      pfam06371
      Location:45232
      Drf_GBD; Diaphanous GTPase-binding Domain
      pfam10211
      Location:450507
      Ax_dynein_light; Axonemal dynein light chain
    3. NM_172464.3NP_766052.2  disheveled-associated activator of morphogenesis 1 isoform a

      See identical proteins and their annotated locations for NP_766052.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (a).
      Source sequence(s)
      AC124356, AK033683, AK162231, BC076585
      Consensus CDS
      CCDS25964.1
      UniProtKB/Swiss-Prot
      Q8BPM0
      UniProtKB/TrEMBL
      Q8BTF1
      Related
      ENSMUSP00000152564.1, ENSMUST00000223272.1
      Conserved Domains (4) summary
      pfam02181
      Location:600982
      FH2; Formin Homology 2 Domain
      pfam06367
      Location:235439
      Drf_FH3; Diaphanous FH3 Domain
      pfam06371
      Location:45232
      Drf_GBD; Diaphanous GTPase-binding Domain
      pfam10211
      Location:450507
      Ax_dynein_light; Axonemal dynein light chain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000078.6 Reference GRCm38.p4 C57BL/6J

      Range
      71831047..71992376
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515643.3XP_006515706.1  disheveled-associated activator of morphogenesis 1 isoform X2

      See identical proteins and their annotated locations for XP_006515706.1

      UniProtKB/Swiss-Prot
      Q8BPM0
      Conserved Domains (4) summary
      pfam02181
      Location:600973
      FH2; Formin Homology 2 Domain
      pfam06367
      Location:235439
      Drf_FH3; Diaphanous FH3 Domain
      pfam06371
      Location:45232
      Drf_GBD; Diaphanous GTPase-binding Domain
      pfam10211
      Location:450507
      Ax_dynein_light; Axonemal dynein light chain
    2. XM_006515644.3XP_006515707.1  disheveled-associated activator of morphogenesis 1 isoform X2

      See identical proteins and their annotated locations for XP_006515707.1

      UniProtKB/Swiss-Prot
      Q8BPM0
      Conserved Domains (4) summary
      pfam02181
      Location:600973
      FH2; Formin Homology 2 Domain
      pfam06367
      Location:235439
      Drf_FH3; Diaphanous FH3 Domain
      pfam06371
      Location:45232
      Drf_GBD; Diaphanous GTPase-binding Domain
      pfam10211
      Location:450507
      Ax_dynein_light; Axonemal dynein light chain
    3. XM_006515642.2XP_006515705.1  disheveled-associated activator of morphogenesis 1 isoform X1

      See identical proteins and their annotated locations for XP_006515705.1

      UniProtKB/Swiss-Prot
      Q8BPM0
      Conserved Domains (4) summary
      pfam02181
      Location:600982
      FH2; Formin Homology 2 Domain
      pfam06367
      Location:235439
      Drf_FH3; Diaphanous FH3 Domain
      pfam06371
      Location:45232
      Drf_GBD; Diaphanous GTPase-binding Domain
      pfam10211
      Location:450507
      Ax_dynein_light; Axonemal dynein light chain
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