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    Stip1 stress-induced phosphoprotein 1 [ Mus musculus (house mouse) ]

    Gene ID: 20867, updated on 26-Jul-2021

    Summary

    Official Symbol
    Stip1provided by MGI
    Official Full Name
    stress-induced phosphoprotein 1provided by MGI
    Primary source
    MGI:MGI:109130
    See related
    Ensembl:ENSMUSG00000024966
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H; ST; p6; Hop; p60; Sti1
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 77.9), placenta adult (RPKM 65.0) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Stip1 in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (6998064..7017394, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (7020696..7040026, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (7095186..7114516, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene nudix (nucleoside diphosphate linked moiety X)-type motif 22 Neighboring gene tRNA phosphotransferase 1 Neighboring gene fermitin family member 3 Neighboring gene predicted gene, 54052 Neighboring gene mono-ADP ribosylhydrolase 1 Neighboring gene RIKEN cDNA 5730409K12 gene Neighboring gene fibronectin leucine rich transmembrane protein 1 Neighboring gene predicted gene, 38621

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables Hsp70 protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables Hsp90 protein binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables Hsp90 protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables chaperone binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein C-terminus binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cellular response to interleukin-7 IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of chaperone complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in myelin sheath HDA PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    stress-induced-phosphoprotein 1
    Names
    Hsp70/Hsp90 organizing protein
    IEF SSP 3521
    hsc70/Hsp90-organizing protein
    mSTI1
    stress-inducible protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_016737.2NP_058017.1  stress-induced-phosphoprotein 1

      See identical proteins and their annotated locations for NP_058017.1

      Status: VALIDATED

      Source sequence(s)
      AK167273, BY387498, CJ155828
      Consensus CDS
      CCDS37901.1
      UniProtKB/Swiss-Prot
      Q60864
      Related
      ENSMUSP00000025918.8, ENSMUST00000025918.9
      Conserved Domains (6) summary
      smart00727
      Location:492531
      STI1; Heat shock chaperonin-binding motif
      smart00028
      Location:300328
      TPR; Tetratricopeptide repeats
      sd00006
      Location:364388
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:394427
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:360425
      TPR_11; TPR repeat
      pfam13424
      Location:255328
      TPR_12; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      6998064..7017394 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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