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    Kntc1 kinetochore associated 1 [ Mus musculus (house mouse) ]

    Gene ID: 208628, updated on 5-Aug-2018

    Summary

    Official Symbol
    Kntc1provided by MGI
    Official Full Name
    kinetochore associated 1provided by MGI
    Primary source
    MGI:MGI:2673709
    See related
    Ensembl:ENSMUSG00000029414 Vega:OTTMUSG00000054741
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    jgl; D330012D13
    Expression
    Biased expression in CNS E11.5 (RPKM 6.8), liver E14 (RPKM 6.3) and 14 other tissues See more
    Orthologs

    Genomic context

    See Kntc1 in Genome Data Viewer
    Location:
    5; 5 F
    Exon count:
    66
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 5 NC_000071.6 (123749690..123821593)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (124199735..124271602)

    Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene polymerase (RNA) II (DNA directed) polypeptide K pseudogene Neighboring gene arginine/serine-rich coiled-coil 2 Neighboring gene hydroxycarboxylic acid receptor 2 Neighboring gene hydrocarboxylic acid receptor 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Spontaneous (1) 
    • Targeted (2) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    cell division IEA
    Inferred from Electronic Annotation
    more info
     
    mitotic cell cycle checkpoint ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    RZZ complex ISO
    Inferred from Sequence Orthology
    more info
     
    actin cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    chromosome, centromeric region IEA
    Inferred from Electronic Annotation
    more info
     
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    kinetochore IEA
    Inferred from Electronic Annotation
    more info
     
    kinetochore microtubule ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    spindle pole ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    kinetochore-associated protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001042421.1NP_001035886.1  kinetochore-associated protein 1

      See identical proteins and their annotated locations for NP_001035886.1

      Status: VALIDATED

      Source sequence(s)
      AC129582, AK172905, BY010626
      Consensus CDS
      CCDS39274.1
      UniProtKB/Swiss-Prot
      Q8C3Y4
      Related
      ENSMUSP00000031366.7, OTTMUSP00000071768, ENSMUST00000031366.11, OTTMUST00000135684
      Conserved Domains (1) summary
      pfam10493
      Location:15822126
      Rod_C; Rough deal protein C-terminal region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000071.6 Reference GRCm38.p4 C57BL/6J

      Range
      123749690..123821593
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006530253.3XP_006530316.1  kinetochore-associated protein 1 isoform X5

    2. XM_006530252.3XP_006530315.1  kinetochore-associated protein 1 isoform X4

    3. XM_006530250.3XP_006530313.1  kinetochore-associated protein 1 isoform X2

      Conserved Domains (1) summary
      pfam10493
      Location:15821962
      Rod_C; Rough deal protein C-terminal region
    4. XM_006530249.1XP_006530312.1  kinetochore-associated protein 1 isoform X1

      Conserved Domains (1) summary
      pfam10493
      Location:14301974
      Rod_C; Rough deal protein C-terminal region
    5. XM_006530251.3XP_006530314.1  kinetochore-associated protein 1 isoform X3

      Conserved Domains (1) summary
      pfam10493
      Location:7791323
      Rod_C; Rough deal protein C-terminal region
    6. XM_006530254.2XP_006530317.1  kinetochore-associated protein 1 isoform X6

      Conserved Domains (1) summary
      pfam10493
      Location:6761220
      Rod_C; Rough deal protein C-terminal region
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