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    Etl4 enhancer trap locus 4 [ Mus musculus (house mouse) ]

    Gene ID: 208618, updated on 5-Aug-2018

    Summary

    Official Symbol
    Etl4provided by MGI
    Official Full Name
    enhancer trap locus 4provided by MGI
    Primary source
    MGI:MGI:95454
    See related
    Ensembl:ENSMUSG00000036617 Vega:OTTMUSG00000011450
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Skt; Etl-4; BC026657; 6620402G01Rik; 9430077C05Rik; E330027G05Rik
    Expression
    Ubiquitous expression in cortex adult (RPKM 4.1), frontal lobe adult (RPKM 3.9) and 28 other tissues See more
    Orthologs

    Genomic context

    See Etl4 in Genome Data Viewer
    Location:
    2 A3; 2 14.27 cM
    Exon count:
    31
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 2 NC_000068.7 (19909763..20810535)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (20211540..20732162)

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene GTPase activating protein (SH3 domain) binding protein 2 pseudogene Neighboring gene OTU domain containing 1 Neighboring gene Ngfi-A binding protein 1 pseudogene Neighboring gene predicted gene 13363 Neighboring gene voltage-dependent anion channel 1 pseudogene Neighboring gene mitochondrial ribosomal protein S5 pseudogene Neighboring gene predicted gene 17171 Neighboring gene Rho GTPase activating protein 21 Neighboring gene predicted gene 13375

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    embryonic skeletal system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081006.1NP_001074475.1  sickle tail protein isoform c

      See identical proteins and their annotated locations for NP_001074475.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (c) represents the longest transcript and it encodes the longest protein (isoform c).
      Source sequence(s)
      AB125594, AK147510, AL929100, BC158051, CF744489
      Consensus CDS
      CCDS38053.1
      UniProtKB/Swiss-Prot
      A2AQ25
      UniProtKB/TrEMBL
      B2RY09, E9QAU4
      Related
      ENSMUSP00000110274.1, ENSMUST00000114627.7
      Conserved Domains (1) summary
      pfam03915
      Location:239310
      AIP3; Actin interacting protein 3
    2. NM_001177630.2NP_001171101.2  sickle tail protein isoform d

      Status: VALIDATED

      Description
      Transcript Variant: This variant (d) has multiple differences, compared to variant c. These differences result in a distinct 5' UTR and cause translation initiation at a downstream start codon, compared to variant c. The encoded protein (isoform d) is shorter when it is compared to isoform c.
      Source sequence(s)
      AB125594, AL929100, BB040164, BC158051
      Consensus CDS
      CCDS50509.1
      UniProtKB/Swiss-Prot
      A2AQ25
      UniProtKB/TrEMBL
      B2RY09, D3Z781
      Related
      ENSMUSP00000110251.2, OTTMUSP00000052745, ENSMUST00000114604.8, OTTMUST00000094730
      Conserved Domains (1) summary
      pfam03915
      Location:188259
      AIP3; Actin interacting protein 3
    3. NM_001177631.1NP_001171102.1  sickle tail protein isoform e

      Status: VALIDATED

      Description
      Transcript Variant: This variant (e) has multiple differences, compared to variant c. These differences result in a distinct 5' UTR and cause translation initiation at a downstream start codon, compared to variant c. The encoded protein (isoform e) is shorter when it is compared to isoform c.
      Source sequence(s)
      AK147510, AL844538, AL929100, BC158051, BC172143
      UniProtKB/TrEMBL
      B2RY09
      Conserved Domains (1) summary
      pfam03915
      Location:188259
      AIP3; Actin interacting protein 3
    4. NM_029895.4NP_084171.2  sickle tail protein isoform b

      See identical proteins and their annotated locations for NP_084171.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (b) has multiple differences, compared to variant c. These differences result in a distinct 5' UTR and cause translation initiation at a downstream start codon, compared to variant c. The encoded protein (isoform b) is shorter when it is compared to isoform c.
      Source sequence(s)
      AB125595, AL929100
      Consensus CDS
      CCDS50510.1
      UniProtKB/Swiss-Prot
      A2AQ25
      Related
      ENSMUSP00000110261.1, OTTMUSP00000012255, ENSMUST00000114614.7, OTTMUST00000026840
      Conserved Domains (1) summary
      pfam03915
      Location:188259
      AIP3; Actin interacting protein 3
    5. NM_178059.5NP_835160.2  sickle tail protein isoform a

      See identical proteins and their annotated locations for NP_835160.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (a) has multiple differences, compared to variant c. These differences result in a distinct 5' UTR and cause translation initiation at a downstream start codon, compared to variant c. The encoded protein (isoform a) is shorter when it is compared to isoform c.
      Source sequence(s)
      AB125594, AL929100
      Consensus CDS
      CCDS50511.1
      UniProtKB/Swiss-Prot
      A2AQ25
      Related
      ENSMUSP00000041431.4, OTTMUSP00000012233, ENSMUST00000045555.10, OTTMUST00000026794
      Conserved Domains (1) summary
      pfam03915
      Location:188259
      AIP3; Actin interacting protein 3

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38.p4 C57BL/6J

      Range
      19909763..20810535
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006497430.3XP_006497493.1  sickle tail protein isoform X15

      Conserved Domains (1) summary
      pfam03915
      Location:239310
      AIP3; Actin interacting protein 3
    2. XM_006497408.3XP_006497471.1  sickle tail protein isoform X1

      See identical proteins and their annotated locations for XP_006497471.1

      UniProtKB/TrEMBL
      E9QAU4
      Conserved Domains (1) summary
      pfam03915
      Location:239310
      AIP3; Actin interacting protein 3
    3. XM_006497414.2XP_006497477.1  sickle tail protein isoform X3

      Conserved Domains (1) summary
      pfam03915
      Location:239310
      AIP3; Actin interacting protein 3
    4. XM_006497410.3XP_006497473.1  sickle tail protein isoform X2

      Conserved Domains (1) summary
      pfam03915
      Location:239310
      AIP3; Actin interacting protein 3
    5. XM_006497426.2XP_006497489.1  sickle tail protein isoform X11

      Conserved Domains (1) summary
      pfam03915
      Location:239310
      AIP3; Actin interacting protein 3
    6. XM_006497428.2XP_006497491.1  sickle tail protein isoform X13

      Conserved Domains (1) summary
      pfam03915
      Location:239310
      AIP3; Actin interacting protein 3
    7. XM_017316831.1XP_017172320.1  sickle tail protein isoform X14

    8. XM_006497427.2XP_006497490.1  sickle tail protein isoform X12

      Conserved Domains (1) summary
      pfam03915
      Location:239310
      AIP3; Actin interacting protein 3
    9. XM_011238967.2XP_011237269.1  sickle tail protein isoform X8

      Conserved Domains (1) summary
      pfam03915
      Location:108179
      AIP3; Actin interacting protein 3
    10. XM_006497415.3XP_006497478.1  sickle tail protein isoform X4

      See identical proteins and their annotated locations for XP_006497478.1

      UniProtKB/Swiss-Prot
      A2AQ25
      Related
      ENSMUSP00000066170.3, OTTMUSP00000012256, ENSMUST00000066509.9, OTTMUST00000026842
      Conserved Domains (1) summary
      pfam03915
      Location:188259
      AIP3; Actin interacting protein 3
    11. XM_006497419.2XP_006497482.1  sickle tail protein isoform X6

      Conserved Domains (1) summary
      pfam03915
      Location:38109
      AIP3; Actin interacting protein 3
    12. XM_006497417.3XP_006497480.1  sickle tail protein isoform X5

      Conserved Domains (1) summary
      pfam03915
      Location:104175
      AIP3; Actin interacting protein 3
    13. XM_017316833.1XP_017172322.1  sickle tail protein isoform X17

    14. XM_017316832.1XP_017172321.1  sickle tail protein isoform X16

    15. XM_006497422.3XP_006497485.1  sickle tail protein isoform X9

      See identical proteins and their annotated locations for XP_006497485.1

      Conserved Domains (2) summary
      PHA02682
      Location:16103
      PHA02682; ORF080 virion core protein; Provisional
      pfam09606
      Location:549666
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    16. XM_006497424.3XP_006497487.1  sickle tail protein isoform X10

      UniProtKB/Swiss-Prot
      A2AQ25
      Related
      ENSMUSP00000110255.1, OTTMUSP00000012342, ENSMUST00000114608.2, OTTMUST00000027092
      Conserved Domains (2) summary
      PHA02682
      Location:16103
      PHA02682; ORF080 virion core protein; Provisional
      pfam09606
      Location:514631
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    17. XM_006497420.3XP_006497483.1  sickle tail protein isoform X7

      Conserved Domains (2) summary
      PHA02682
      Location:132219
      PHA02682; ORF080 virion core protein; Provisional
      pfam09606
      Location:665782
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    18. XM_006497423.3XP_006497486.1  sickle tail protein isoform X9

      See identical proteins and their annotated locations for XP_006497486.1

      Conserved Domains (2) summary
      PHA02682
      Location:16103
      PHA02682; ORF080 virion core protein; Provisional
      pfam09606
      Location:549666
      Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
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