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    Stag1 stromal antigen 1 [ Mus musculus (house mouse) ]

    Gene ID: 20842, updated on 23-Jun-2021

    Summary

    Official Symbol
    Stag1provided by MGI
    Official Full Name
    stromal antigen 1provided by MGI
    Primary source
    MGI:MGI:1098658
    See related
    Ensembl:ENSMUSG00000037286
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SA; Scc; SA-1; Scc3; AU045003
    Expression
    Broad expression in placenta adult (RPKM 8.6), CNS E11.5 (RPKM 8.5) and 22 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Stag1 in Genome Data Viewer
    Location:
    9; 9 E3.3- E4
    Exon count:
    39
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (100479762..100840597)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (100597709..100958544)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (100544042..100858963)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene non-catalytic region of tyrosine kinase adaptor protein 1 Neighboring gene predicted gene, 46139 Neighboring gene solute carrier family 35, member G2 Neighboring gene predicted gene 8661 Neighboring gene adaptor-related protein complex 2, beta 1 subunit pseudogene Neighboring gene uncharacterized LOC118567727 Neighboring gene propionyl Coenzyme A carboxylase, beta polypeptide Neighboring gene brain expressed X-linked 2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within chromosome segregation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic spindle assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sister chromatid cohesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in chromatin ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    part_of cohesin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of cohesin complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitotic spindle pole ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nuclear matrix ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    cohesin subunit SA-1
    Names
    SCC3 homolog 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001357264.1NP_001344193.1  cohesin subunit SA-1 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1.
      Source sequence(s)
      AC115355, AC134825, AC146297, AC147565
      Conserved Domains (1) summary
      pfam08514
      Location:23131
      STAG; STAG domain
    2. NM_001357265.1NP_001344194.1  cohesin subunit SA-1 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
      Source sequence(s)
      AC115355, AC134825, AC146297, AC147565
      Related
      ENSMUSP00000120974.2, ENSMUST00000146934.8
    3. NM_009282.4NP_033308.2  cohesin subunit SA-1 isoform 1

      See identical proteins and their annotated locations for NP_033308.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AC134825, AK043215, BC062954
      Consensus CDS
      CCDS23441.1
      UniProtKB/Swiss-Prot
      Q9D3E6
      Related
      ENSMUSP00000116205.2, ENSMUST00000129269.8
      Conserved Domains (2) summary
      pfam08514
      Location:160268
      STAG; STAG domain
      pfam14621
      Location:358
      RFX5_DNA_bdg; RFX5 DNA-binding domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      100479762..100840597
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006510924.4XP_006510987.1  cohesin subunit SA-1 isoform X1

      See identical proteins and their annotated locations for XP_006510987.1

      UniProtKB/Swiss-Prot
      Q9D3E6
      Conserved Domains (2) summary
      pfam08514
      Location:160268
      STAG; STAG domain
      pfam14621
      Location:358
      RFX5_DNA_bdg; RFX5 DNA-binding domain
    2. XM_030244173.2XP_030100033.1  cohesin subunit SA-1 isoform X3

      Conserved Domains (1) summary
      pfam08514
      Location:63171
      STAG; STAG domain
    3. XM_006510925.2XP_006510988.1  cohesin subunit SA-1 isoform X2

      UniProtKB/TrEMBL
      F8WHU7
      Related
      ENSMUSP00000040724.7, ENSMUST00000041418.13
      Conserved Domains (2) summary
      pfam08514
      Location:160268
      STAG; STAG domain
      pfam14621
      Location:358
      RFX5_DNA_bdg; RFX5 DNA-binding domain
    4. XM_011242692.3XP_011240994.1  cohesin subunit SA-1 isoform X6

      Conserved Domains (2) summary
      pfam08514
      Location:160268
      STAG; STAG domain
      pfam14621
      Location:358
      RFX5_DNA_bdg; RFX5 DNA-binding domain
    5. XM_036154768.1XP_036010661.1  cohesin subunit SA-1 isoform X5

      Conserved Domains (1) summary
      pfam08514
      Location:23131
      STAG; STAG domain
    6. XM_006510923.4XP_006510986.1  cohesin subunit SA-1 isoform X1

      See identical proteins and their annotated locations for XP_006510986.1

      UniProtKB/Swiss-Prot
      Q9D3E6
      Conserved Domains (2) summary
      pfam08514
      Location:160268
      STAG; STAG domain
      pfam14621
      Location:358
      RFX5_DNA_bdg; RFX5 DNA-binding domain
    7. XM_036154767.1XP_036010660.1  cohesin subunit SA-1 isoform X4

      Conserved Domains (1) summary
      pfam08514
      Location:23131
      STAG; STAG domain
    8. XM_030244172.2XP_030100032.1  cohesin subunit SA-1 isoform X1

      Conserved Domains (2) summary
      pfam08514
      Location:160268
      STAG; STAG domain
      pfam14621
      Location:358
      RFX5_DNA_bdg; RFX5 DNA-binding domain
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