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    Shcbp1 Shc SH2-domain binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 20419, updated on 2-Oct-2021

    Summary

    Official Symbol
    Shcbp1provided by MGI
    Official Full Name
    Shc SH2-domain binding protein 1provided by MGI
    Primary source
    MGI:MGI:1338802
    See related
    Ensembl:ENSMUSG00000022322
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mPAL
    Expression
    Biased expression in CNS E11.5 (RPKM 16.0), liver E14 (RPKM 13.9) and 10 other tissues See more
    Orthologs
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    Genomic context

    See Shcbp1 in Genome Data Viewer
    Location:
    8; 8 A1.1
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (4785976..4829567, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (4735976..4779567, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (4735980..4779534, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene high mobility group protein 1 pseudogene Neighboring gene predicted gene, 39124 Neighboring gene protein kinase inhibitor, gamma pseudogene Neighboring gene ribosomal protein L22 pseudogene Neighboring gene ribosomal protein L21, pseudogene 14

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SH2 domain binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    SHC SH2 domain-binding protein 1
    Names
    SHC-binding protein
    protein expressed in activated lymphocytes

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011369.3NP_035499.1  SHC SH2 domain-binding protein 1

      See identical proteins and their annotated locations for NP_035499.1

      Status: VALIDATED

      Source sequence(s)
      AF017152, AK051205, BQ747009
      Consensus CDS
      CCDS22088.1
      UniProtKB/Swiss-Prot
      Q9Z179
      Related
      ENSMUSP00000022945.8, ENSMUST00000022945.9
      Conserved Domains (1) summary
      pfam13229
      Location:413559
      Beta_helix; Right handed beta helix region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      4785976..4829567 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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