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    Zfp106 zinc finger protein 106 [ Mus musculus (house mouse) ]

    Gene ID: 20402, updated on 16-Jul-2021

    Summary

    Official Symbol
    Zfp106provided by MGI
    Official Full Name
    zinc finger protein 106provided by MGI
    Primary source
    MGI:MGI:1270153
    See related
    Ensembl:ENSMUSG00000027288
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    s; H3; H3a; Cd-1; Sh3b; sirm; Sh3bp3; Znf106; D2Dcr28; zfp-106; EyeLinc12
    Expression
    Ubiquitous expression in heart adult (RPKM 47.5), frontal lobe adult (RPKM 16.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Zfp106 in Genome Data Viewer
    Location:
    2 E5; 2 60.37 cM
    Exon count:
    22
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (120337301..120394367, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (120506820..120563864, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (120332566..120389567, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene transmembrane protein 87A Neighboring gene glucosidase, alpha; neutral C Neighboring gene RIKEN cDNA 4931402G19 gene Neighboring gene calpain 3 Neighboring gene synaptosomal-associated protein 23 Neighboring gene leucine rich repeat containing 57 Neighboring gene HAUS augmin-like complex, subunit 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables SH3 domain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables SH3 domain binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables opioid peptide activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in insulin receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within insulin receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 106
    Names
    H3a minor histocompatibility antigen
    SH3-domain binding protein 3
    zinc finger protein 474

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011743.3NP_035873.2  zinc finger protein 106

      Status: VALIDATED

      Source sequence(s)
      AL772299, AL935121
      Consensus CDS
      CCDS16621.1
      UniProtKB/TrEMBL
      R4GML0
      Related
      ENSMUSP00000055602.7, ENSMUST00000055241.13
      Conserved Domains (4) summary
      cd00200
      Location:15301807
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00020
      Location:729
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam05109
      Location:530681
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00039
      Location:15801619
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      120337301..120394367 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006499044.5XP_006499107.1  zinc finger protein 106 isoform X3

      Conserved Domains (2) summary
      cd00200
      Location:7411018
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:791830
      7WD40; WD40 repeat [structural motif]
    2. XM_006499042.5XP_006499105.1  zinc finger protein 106 isoform X2

      Conserved Domains (3) summary
      cd00200
      Location:14641741
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam05109
      Location:464615
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00039
      Location:15141553
      7WD40; WD40 repeat [structural motif]
    3. XM_030248878.2XP_030104738.1  zinc finger protein 106 isoform X1

      Conserved Domains (4) summary
      cd00200
      Location:15301807
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00020
      Location:729
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam05109
      Location:530681
      Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
      sd00039
      Location:15801619
      7WD40; WD40 repeat [structural motif]
    4. XM_030248880.1XP_030104740.1  zinc finger protein 106 isoform X3

      Conserved Domains (2) summary
      cd00200
      Location:7411018
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:791830
      7WD40; WD40 repeat [structural motif]
    5. XM_036159870.1XP_036015763.1  zinc finger protein 106 isoform X4

      Conserved Domains (2) summary
      cd00200
      Location:314591
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:364403
      7WD40; WD40 repeat [structural motif]

    RNA

    1. XR_004939180.1 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_009165.1: Suppressed sequence

      Description
      NM_009165.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
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