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    Sec61g SEC61, gamma subunit [ Mus musculus (house mouse) ]

    Gene ID: 20335, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sec61gprovided by MGI
    Official Full Name
    SEC61, gamma subunitprovided by MGI
    Primary source
    MGI:MGI:1202066
    See related
    Ensembl:ENSMUSG00000078974
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Expression
    Broad expression in liver E14 (RPKM 73.5), placenta adult (RPKM 63.1) and 24 other tissues See more
    Orthologs
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    Genomic context

    See Sec61g in Genome Data Viewer
    Location:
    11; 11 A2
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (16451638..16458484, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (16501638..16508484, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (16401641..16408487, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene V-set and transmembrane domain containing 2A Neighboring gene predicted gene 12012 Neighboring gene thymoma viral proto-oncogene 2, pseudogene Neighboring gene VISTA enhancer mm1103

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein-transporting ATPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in posttranslational protein targeting to membrane, translocation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein targeting IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of Ssh1 translocon complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 

    General protein information

    Preferred Names
    protein transport protein Sec61 subunit gamma

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109971.1NP_001103441.1  protein transport protein Sec61 subunit gamma isoform 2

      See identical proteins and their annotated locations for NP_001103441.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) includes an alternate segment in exon 1, compared to variant 1. This causes translation initiation at a downstream AUG and an isoform (2) with a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AK012393, AK012644, BY468217, CO808059
      Consensus CDS
      CCDS48755.1
      UniProtKB/Swiss-Prot
      P60060
      UniProtKB/TrEMBL
      Q5SWJ8
      Related
      ENSMUSP00000137362.2, ENSMUST00000178855.8
      Conserved Domains (1) summary
      cl00481
      Location:1268
      SecE; SecE/Sec61-gamma subunits of protein translocation complex
    2. NM_001109972.1NP_001103442.1  protein transport protein Sec61 subunit gamma isoform 2

      See identical proteins and their annotated locations for NP_001103442.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) includes an alternate segment in exon 1, compared to variant 1. This causes translation initiation at a downstream AUG and an isoform (2) with a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AK012644, AV456975, CO808059
      Consensus CDS
      CCDS48755.1
      UniProtKB/Swiss-Prot
      P60060
      UniProtKB/TrEMBL
      Q5SWJ8
      Related
      ENSMUSP00000105270.2, ENSMUST00000109642.8
      Conserved Domains (1) summary
      cl00481
      Location:1268
      SecE; SecE/Sec61-gamma subunits of protein translocation complex
    3. NM_011343.3NP_035473.2  protein transport protein Sec61 subunit gamma isoform 1

      See identical proteins and their annotated locations for NP_035473.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK012644, CO808059
      Consensus CDS
      CCDS48756.1
      UniProtKB/Swiss-Prot
      P60060
      UniProtKB/TrEMBL
      G3UWH0
      Related
      ENSMUSP00000132348.2, ENSMUST00000166950.8
      Conserved Domains (1) summary
      cl00481
      Location:44100
      SecE; SecE/Sec61-gamma subunits of protein translocation complex

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      16451638..16458484 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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