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    Sec23a SEC23 homolog A, COPII coat complex component [ Mus musculus (house mouse) ]

    Gene ID: 20334, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sec23aprovided by MGI
    Official Full Name
    SEC23 homolog A, COPII coat complex componentprovided by MGI
    Primary source
    MGI:MGI:1349635
    See related
    Ensembl:ENSMUSG00000020986
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sec2; Msec2; Msec23; Sec23r
    Expression
    Ubiquitous expression in placenta adult (RPKM 26.3), limb E14.5 (RPKM 22.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Sec23a in Genome Data Viewer
    Location:
    12; 12 C1
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (59005170..59058803, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (58958384..59012017, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (60059371..60113004, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene DEAD (Asp-Glu-Ala-Asp) box polypeptide 21 pseudogene Neighboring gene PRELI domain containing 1 pseudogene Neighboring gene gem nuclear organelle associated protein 2 Neighboring gene predicted gene, 22973

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of COPII vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of COPII vesicle coat ISO
    Inferred from Sequence Orthology
    more info
     
    located_in COPII-coated ER to Golgi transport vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in ER to Golgi transport vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum exit site IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum exit site ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane TAS
    Traceable Author Statement
    more info
     
    located_in extrinsic component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    protein transport protein Sec23A
    Names
    SEC23-related protein A

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001361956.1NP_001348885.1  protein transport protein Sec23A

      Status: VALIDATED

      Source sequence(s)
      AC153654, AY082671, BY760439, BY778724, BY789138
      Consensus CDS
      CCDS25931.1
      Conserved Domains (1) summary
      PLN00162
      Location:12763
      PLN00162; transport protein sec23; Provisional
    2. NM_009147.2NP_033173.2  protein transport protein Sec23A

      See identical proteins and their annotated locations for NP_033173.2

      Status: VALIDATED

      Source sequence(s)
      AK028152, BC034610, BY760439
      Consensus CDS
      CCDS25931.1
      UniProtKB/Swiss-Prot
      Q01405
      UniProtKB/TrEMBL
      Q8C1E4
      Related
      ENSMUSP00000021375.6, ENSMUST00000021375.12
      Conserved Domains (1) summary
      PLN00162
      Location:12763
      PLN00162; transport protein sec23; Provisional

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      59005170..59058803 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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