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    Sec22b SEC22 homolog B, vesicle trafficking protein [ Mus musculus (house mouse) ]

    Gene ID: 20333, updated on 4-Nov-2018

    Summary

    Official Symbol
    Sec22bprovided by MGI
    Official Full Name
    SEC22 homolog B, vesicle trafficking proteinprovided by MGI
    Primary source
    MGI:MGI:1338759
    See related
    Ensembl:ENSMUSG00000027879 Vega:OTTMUSG00000028867
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C81333; ERS-24; Sec22l1; AA517334; AI480645; 4930564D15Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 47.1), limb E14.5 (RPKM 29.5) and 28 other tissues See more
    Orthologs

    Genomic context

    See Sec22b in Genome Data Viewer
    Location:
    3; 3 F2.2
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 3 NC_000069.6 (97901227..97922318)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (97705150..97726241)

    Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 4D interacting protein (myomegalin) Neighboring gene predicted gene, 46816 Neighboring gene transformer 2 alpha homolog pseudogene Neighboring gene predicted gene 5544 Neighboring gene notch 2 Neighboring gene predicted gene, 40103

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    SNAP receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    syntaxin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    ER to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ER to Golgi vesicle-mediated transport TAS
    Traceable Author Statement
    more info
    PubMed 
    negative regulation of autophagosome assembly ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of protein catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    retrograde vesicle-mediated transport, Golgi to ER IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    vesicle fusion with Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    vesicle-mediated transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    ER to Golgi transport vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ER to Golgi transport vesicle membrane ISO
    Inferred from Sequence Orthology
    more info
     
    Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Golgi membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    endoplasmic reticulum-Golgi intermediate compartment ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    vesicle-trafficking protein SEC22b
    Names
    ER-Golgi SNARE of 24 kDa
    ERS24
    SEC22 vesicle trafficking protein homolog B
    SEC22 vesicle trafficking protein-like 1
    mSec22b

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011342.4NP_035472.1  vesicle-trafficking protein SEC22b precursor

      See identical proteins and their annotated locations for NP_035472.1

      Status: PROVISIONAL

      Source sequence(s)
      AC131746
      Consensus CDS
      CCDS17658.1
      UniProtKB/Swiss-Prot
      O08547
      Related
      ENSMUSP00000029476.2, OTTMUSP00000036640, ENSMUST00000029476.8, OTTMUST00000071496
      Conserved Domains (2) summary
      cd15866
      Location:132195
      R-SNARE_SEC22; SNARE motif of SEC22
      pfam13774
      Location:37114
      Longin; Regulated-SNARE-like domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000069.6 Reference GRCm38.p4 C57BL/6J

      Range
      97901227..97922318
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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