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    Sar1a secretion associated Ras related GTPase 1A [ Mus musculus (house mouse) ]

    Gene ID: 20224, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sar1aprovided by MGI
    Official Full Name
    secretion associated Ras related GTPase 1Aprovided by MGI
    Primary source
    MGI:MGI:98230
    See related
    Ensembl:ENSMUSG00000020088
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S; Sara; Sara1; 1600019H17Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 41.8), bladder adult (RPKM 39.2) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Sar1a in Genome Data Viewer
    Location:
    10; 10 B4
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (61516064..61529076)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (61680285..61693297)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (61143069..61156045)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene neuropeptide FF receptor 1 Neighboring gene pyrophosphatase (inorganic) 1 Neighboring gene RIKEN cDNA 1700022H01 gene Neighboring gene trypsin domain containing 1 Neighboring gene apoptosis-inducing factor, mitochondrion-associated 2 Neighboring gene macroH2A.2 histone

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of COPII vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of COPII vesicle coat ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in endoplasmic reticulum exit site IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in sarcoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    GTP-binding protein SAR1a
    Names
    SAR1 gene homolog A
    SAR1a gene homolog 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358487.1NP_001345416.1  GTP-binding protein SAR1a

      Status: VALIDATED

      Source sequence(s)
      AW490903, BY264777, CN692595, CN702712, CO426359, CX768065, DV662848
      Consensus CDS
      CCDS23883.1
      Conserved Domains (1) summary
      cd00879
      Location:3197
      Sar1; Sar1 is an essential component of COPII vesicle coats
    2. NM_001358488.1NP_001345417.1  GTP-binding protein SAR1a

      Status: VALIDATED

      Source sequence(s)
      AW490903, BY264777, BY768079, CN692595, CN702712, CO426359, CX768065, DV662848
      Consensus CDS
      CCDS23883.1
      Conserved Domains (1) summary
      cd00879
      Location:3197
      Sar1; Sar1 is an essential component of COPII vesicle coats
    3. NM_009120.3NP_033146.1  GTP-binding protein SAR1a

      See identical proteins and their annotated locations for NP_033146.1

      Status: VALIDATED

      Source sequence(s)
      AK157843, AW490903, BY264777, CN702712
      Consensus CDS
      CCDS23883.1
      UniProtKB/TrEMBL
      Q99JZ4
      Related
      ENSMUSP00000020285.9, ENSMUST00000020285.10
      Conserved Domains (1) summary
      cd00879
      Location:3197
      Sar1; Sar1 is an essential component of COPII vesicle coats

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      61516064..61529076
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030244964.2XP_030100824.1  GTP-binding protein SAR1a isoform X1

      Conserved Domains (1) summary
      cd00879
      Location:3197
      Sar1; Sar1 is an essential component of COPII vesicle coats
    2. XM_030244965.2XP_030100825.1  GTP-binding protein SAR1a isoform X1

      Conserved Domains (1) summary
      cd00879
      Location:3197
      Sar1; Sar1 is an essential component of COPII vesicle coats
    3. XM_036155710.1XP_036011603.1  GTP-binding protein SAR1a isoform X1

      Related
      ENSMUSP00000151383.2, ENSMUST00000219506.2
      Conserved Domains (1) summary
      cd00879
      Location:3197
      Sar1; Sar1 is an essential component of COPII vesicle coats
    4. XM_006513401.4XP_006513464.1  GTP-binding protein SAR1a isoform X1

      See identical proteins and their annotated locations for XP_006513464.1

      UniProtKB/TrEMBL
      Q99JZ4
      Conserved Domains (1) summary
      cd00879
      Location:3197
      Sar1; Sar1 is an essential component of COPII vesicle coats
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