Format

Send to:

Choose Destination
    • Showing Current items.

    Rrm1 ribonucleotide reductase M1 [ Mus musculus (house mouse) ]

    Gene ID: 20133, updated on 5-Aug-2018

    Summary

    Official Symbol
    Rrm1provided by MGI
    Official Full Name
    ribonucleotide reductase M1provided by MGI
    Primary source
    MGI:MGI:98180
    See related
    Ensembl:ENSMUSG00000030978 Vega:OTTMUSG00000060506
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RnrM1
    Expression
    Broad expression in liver E14 (RPKM 64.2), liver E14.5 (RPKM 56.2) and 16 other tissues See more
    Orthologs

    Genomic context

    See Rrm1 in Genome Data Viewer
    Location:
    7 E3; 7 54.72 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 7 NC_000073.6 (102441695..102469771)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (109590209..109618285)

    Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene ras homolog family member G Neighboring gene stromal interaction molecule 1 Neighboring gene methyltransferase like 6 pseudogene Neighboring gene predicted gene, 45996 Neighboring gene olfactory receptor 543

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    disordered domain specific binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    purine nucleotide binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA replication IEA
    Inferred from Electronic Annotation
    more info
     
    deoxyribonucleotide biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    deoxyribonucleotide biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    oxidation-reduction process IEA
    Inferred from Electronic Annotation
    more info
     
    protein complex oligomerization IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein heterotetramerization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    protein heterotetramerization IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    cell projection ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     
    ribonucleoside-diphosphate reductase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    ribonucleoside-diphosphate reductase complex IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 

    General protein information

    Preferred Names
    ribonucleoside-diphosphate reductase large subunit
    Names
    ribonucleoside-diphosphate reductase subunit M1
    ribonucleotide reductase large subunit
    NP_033129.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009103.3NP_033129.2  ribonucleoside-diphosphate reductase large subunit

      See identical proteins and their annotated locations for NP_033129.2

      Status: VALIDATED

      Source sequence(s)
      AC132096, AK168586
      Consensus CDS
      CCDS40049.1
      UniProtKB/Swiss-Prot
      P07742
      Related
      ENSMUSP00000033283.9, OTTMUSP00000076994, ENSMUST00000033283.9, OTTMUST00000148020
      Conserved Domains (3) summary
      cd01679
      Location:167741
      RNR_I; Class I ribonucleotide reductase
      PLN02437
      Location:1792
      PLN02437; ribonucleoside--diphosphate reductase large subunit
      pfam03477
      Location:189
      ATP-cone; ATP cone domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000073.6 Reference GRCm38.p4 C57BL/6J

      Range
      102441695..102469771
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center