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    Rps6 ribosomal protein S6 [ Mus musculus (house mouse) ]

    Gene ID: 20104, updated on 5-Aug-2018

    Summary

    Official Symbol
    Rps6provided by MGI
    Official Full Name
    ribosomal protein S6provided by MGI
    Primary source
    MGI:MGI:98159
    See related
    Ensembl:ENSMUSG00000028495 Vega:OTTMUSG00000007781
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S6R
    Expression
    Ubiquitous expression in bladder adult (RPKM 484.2), CNS E11.5 (RPKM 432.7) and 25 other tissues See more
    Orthologs

    Genomic context

    See Rps6 in Genome Data Viewer
    Location:
    4; 4 C4
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 4 NC_000070.6 (86854099..86857367, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (86500003..86503271, complement)

    Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 42312 Neighboring gene DENN/MADD domain containing 4C Neighboring gene ribosomal protein L7A pseudogene Neighboring gene alkaline ceramidase 2 Neighboring gene solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 Neighboring gene cadherin-2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC102571, MGC103209

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    G1/S transition of mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    T cell differentiation in thymus IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    T cell differentiation in thymus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    T cell proliferation involved in immune response IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    T cell proliferation involved in immune response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    TOR signaling ISO
    Inferred from Sequence Orthology
    more info
     
    activation-induced cell death of T cells IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    erythrocyte development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    gastrulation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    gastrulation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    glucose homeostasis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    mammalian oogenesis stage IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mitotic cell cycle checkpoint IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    placenta development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    rRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    rRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    ribosomal small subunit biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    cell body ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasmic ribonucleoprotein granule ISO
    Inferred from Sequence Orthology
    more info
     
    cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    polysome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    40S ribosomal protein S6
    Names
    phosphoprotein NP33

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009096.3NP_033122.1  40S ribosomal protein S6

      See identical proteins and their annotated locations for NP_033122.1

      Status: PROVISIONAL

      Source sequence(s)
      AK146952
      Consensus CDS
      CCDS18310.1
      UniProtKB/Swiss-Prot
      P62754
      UniProtKB/TrEMBL
      Q5BLK1
      Related
      ENSMUSP00000099878.4, OTTMUSP00000008183, ENSMUST00000102814.4, OTTMUST00000017760
      Conserved Domains (1) summary
      cl00931
      Location:1215
      Ribosomal_S6e; Ribosomal protein S6e

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000070.6 Reference GRCm38.p4 C57BL/6J

      Range
      86854099..86857367 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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