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    Rps6 ribosomal protein S6 [ Mus musculus (house mouse) ]

    Gene ID: 20104, updated on 7-Sep-2021

    Summary

    Official Symbol
    Rps6provided by MGI
    Official Full Name
    ribosomal protein S6provided by MGI
    Primary source
    MGI:MGI:98159
    See related
    Ensembl:ENSMUSG00000028495
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    S; S6R
    Expression
    Ubiquitous expression in bladder adult (RPKM 484.2), CNS E11.5 (RPKM 432.7) and 25 other tissues See more
    Orthologs
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    Genomic context

    See Rps6 in Genome Data Viewer
    Location:
    4; 4 C4
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (86772336..86775604, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (86854099..86857367, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (86500003..86503271, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene DENN/MADD domain containing 4C Neighboring gene predicted gene 6521 Neighboring gene ribosomal protein L7A pseudogene Neighboring gene alkaline ceramidase 2 Neighboring gene solute carrier family 24 (sodium/potassium/calcium exchanger), member 2 Neighboring gene cadherin-2 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC102571, MGC103209

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within G1/S transition of mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within T cell differentiation in thymus IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within T cell differentiation in thymus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within T cell proliferation involved in immune response IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within T cell proliferation involved in immune response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in TOR signaling ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within activation-induced cell death of T cells IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within erythrocyte development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within gastrulation IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within gastrulation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in glucose homeostasis IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within mammalian oogenesis stage IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within mitotic cell cycle checkpoint signaling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within placenta development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within rRNA processing IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in rRNA processing ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within ribosomal small subunit biogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasmic ribonucleoprotein granule ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendrite IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perinuclear region of cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of polysome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    40S ribosomal protein S6
    Names
    phosphoprotein NP33

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009096.3NP_033122.1  40S ribosomal protein S6

      See identical proteins and their annotated locations for NP_033122.1

      Status: PROVISIONAL

      Source sequence(s)
      AK146952
      Consensus CDS
      CCDS18310.1
      UniProtKB/Swiss-Prot
      P62754
      UniProtKB/TrEMBL
      Q5BLK1
      Related
      ENSMUSP00000099878.5, ENSMUST00000102814.5
      Conserved Domains (1) summary
      cl00931
      Location:1215
      Ribosomal_S6e; Ribosomal protein S6e

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      86772336..86775604 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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