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    Rps14 ribosomal protein S14 [ Mus musculus (house mouse) ]

    Gene ID: 20044, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rps14provided by MGI
    Official Full Name
    ribosomal protein S14provided by MGI
    Primary source
    MGI:MGI:98107
    See related
    Ensembl:ENSMUSG00000024608 AllianceGenome:MGI:98107
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2600014J02Rik
    Summary
    A structural constituent of ribosome. Predicted to be involved in several processes, including erythrocyte differentiation; negative regulation of transcription by RNA polymerase II; and ribosomal small subunit biogenesis. Located in mitochondrion. Part of cytosolic small ribosomal subunit. Is active in synapse. Is expressed in early conceptus and metanephros. Human ortholog(s) of this gene implicated in chromosome 5q deletion syndrome. Orthologous to human RPS14 (ribosomal protein S14). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 739.0), liver E14 (RPKM 644.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rps14 in Genome Data Viewer
    Location:
    18 E1; 18 34.4 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (60907668..60911618)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (60774596..60778546)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA G630071F17 gene Neighboring gene VISTA enhancer mm1623 Neighboring gene STARR-positive B cell enhancer ABC_E7590 Neighboring gene N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 Neighboring gene STARR-seq mESC enhancer starr_44724 Neighboring gene STARR-positive B cell enhancer mm9_chr18:60904284-60904585 Neighboring gene CapStarr-seq enhancer MGSCv37_chr18:60935339-60935448 Neighboring gene 40S ribosomal protein S16 pseudogene Neighboring gene STARR-positive B cell enhancer ABC_E2509 Neighboring gene STARR-positive B cell enhancer ABC_E1960 Neighboring gene STARR-positive B cell enhancer ABC_E2510 Neighboring gene STARR-positive B cell enhancer ABC_E8719 Neighboring gene microRNA 5107 Neighboring gene CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (1)  1 citation

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC86125

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables mRNA 5'-UTR binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA 5'-UTR binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    enables translation regulator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation regulator activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in erythrocyte differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in erythrocyte differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in maturation of SSU-rRNA ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in ribosomal small subunit assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ribosomal small subunit assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosomal small subunit assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in translation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in translation at postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in translation at presynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in postsynaptic density IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in presynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of small-subunit processome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    small ribosomal subunit protein uS11
    Names
    40S ribosomal protein S14

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_020600.4NP_065625.2  small ribosomal subunit protein uS11

      See identical proteins and their annotated locations for NP_065625.2

      Status: VALIDATED

      Source sequence(s)
      AK028106, AV490910, BY149058
      Consensus CDS
      CCDS29274.1
      UniProtKB/Swiss-Prot
      P62264, Q544W4
      UniProtKB/TrEMBL
      O70569, Q3UJS5
      Related
      ENSMUSP00000025511.4, ENSMUST00000025511.11
      Conserved Domains (1) summary
      PTZ00129
      Location:1140
      PTZ00129; 40S ribosomal protein S14; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      60907668..60911618
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)