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    Rps12 ribosomal protein S12 [ Mus musculus (house mouse) ]

    Gene ID: 20042, updated on 26-Sep-2022

    Summary

    Official Symbol
    Rps12provided by MGI
    Official Full Name
    ribosomal protein S12provided by MGI
    Primary source
    MGI:MGI:98105
    See related
    Ensembl:ENSMUSG00000061983 AllianceGenome:MGI:98105
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in Golgi apparatus and cytosolic ribosome. Predicted to be part of cytosolic large ribosomal subunit and cytosolic small ribosomal subunit. Orthologous to human RPS12 (ribosomal protein S12). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in liver E14 (RPKM 1796.8), liver E14.5 (RPKM 1660.8) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Rps12 in Genome Data Viewer
    Location:
    10; 10 A4
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (23661081..23663281, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (23785183..23787383, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 35291 Neighboring gene nuclear encoded tRNA trytophan 1 (anticodon CCA) Neighboring gene small nucleolar RNA, C/D box 100 Neighboring gene small nucleolar RNA, H/ACA box 33 Neighboring gene predicted gene, 23130 Neighboring gene solute carrier family 18, subfamily B, member 1 Neighboring gene vanin 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC102111, MGC102112, MGC102499, MGC117504

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in cytoplasmic translation IC
    Inferred by Curator
    more info
    PubMed 
    acts_upstream_of positive regulation of canonical Wnt signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in translation at postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in translation at presynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IC
    Inferred by Curator
    more info
    PubMed 
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of cytosolic small ribosomal subunit IC
    Inferred by Curator
    more info
    PubMed 
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in presynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synapse NAS
    Non-traceable Author Statement
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001407441.1NP_001394370.1  40S ribosomal protein S12 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC160147
      UniProtKB/TrEMBL
      A0A6P5QJZ7, Q6ZWZ6
    2. NM_001407442.1NP_001394371.1  40S ribosomal protein S12 isoform a

      Status: VALIDATED

      Source sequence(s)
      AC160147
      UniProtKB/TrEMBL
      A0A6P5QJZ7, Q6ZWZ6
    3. NM_001407443.1NP_001394372.1  40S ribosomal protein S12 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC160147
    4. NM_001407444.1NP_001394373.1  40S ribosomal protein S12 isoform c

      Status: VALIDATED

      Source sequence(s)
      AC160147
    5. NM_011295.7NP_035425.2  40S ribosomal protein S12 isoform a

      See identical proteins and their annotated locations for NP_035425.2

      Status: VALIDATED

      Source sequence(s)
      AC160147
      Consensus CDS
      CCDS23733.1
      UniProtKB/TrEMBL
      A0A6P5QJZ7, Q6ZWZ6
      Related
      ENSMUSP00000151305.2, ENSMUST00000218107.2
      Conserved Domains (1) summary
      pfam01248
      Location:16111
      Ribosomal_L7Ae; Ribosomal protein L7Ae/L30e/S12e/Gadd45 family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      23661081..23663281 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030244962.1XP_030100822.1  40S ribosomal protein S12 isoform X1

    RNA

    1. XR_003948630.1 RNA Sequence