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    Polr1c polymerase (RNA) I polypeptide C [ Mus musculus (house mouse) ]

    Gene ID: 20016, updated on 8-Jul-2021

    Summary

    Official Symbol
    Polr1cprovided by MGI
    Official Full Name
    polymerase (RNA) I polypeptide Cprovided by MGI
    Primary source
    MGI:MGI:103288
    See related
    Ensembl:ENSMUSG00000067148
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RP; Rpo; 40kD; 40kDa; RPA40; Polr1e; Rpo1-1; AA409007; AA959927; AL024089
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 45.3), limb E14.5 (RPKM 32.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Polr1c in Genome Data Viewer
    Location:
    17; 17 C
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (46554846..46558971, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (46243920..46248045, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 17 NC_000083.5 (46380869..46384994, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene exportin 5 Neighboring gene microRNA 693 Neighboring gene predicted gene, 22474 Neighboring gene Yip1 domain family, member 3 Neighboring gene leucine rich repeat containing 73

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC161175

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    contributes_to DNA-directed 5'-3' RNA polymerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to RNA polymerase I activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    contributes_to RNA polymerase III activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein dimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    involved_in transcription, DNA-templated IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of RNA polymerase I complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of RNA polymerase I complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of RNA polymerase III complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of RNA polymerase III complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    DNA-directed RNA polymerases I and III subunit RPAC1
    Names
    AC40
    DNA-directed RNA polymerase I subunit C
    DNA-directed RNA polymerases I and III 40 kDa polypeptide
    RNA polymerase 1-1 (40 kDa subunit)
    RNA polymerases I and III subunit AC1
    RPC40

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009085.2NP_033111.2  DNA-directed RNA polymerases I and III subunit RPAC1

      See identical proteins and their annotated locations for NP_033111.2

      Status: VALIDATED

      Source sequence(s)
      AK132114, BY267923, CJ207889
      Consensus CDS
      CCDS37632.1
      UniProtKB/Swiss-Prot
      P52432
      Related
      ENSMUSP00000084252.7, ENSMUST00000087026.13
      Conserved Domains (2) summary
      cd07032
      Location:49339
      RNAP_I_II_AC40; AC40 subunit of Eukaryotic RNA polymerase (RNAP) I and RNAP III
      smart00662
      Location:61336
      RPOLD; RNA polymerases D

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      46554846..46558971 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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