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    Rpl7 ribosomal protein L7 [ Mus musculus (house mouse) ]

    Gene ID: 19989, updated on 27-Nov-2024

    Summary

    Official Symbol
    Rpl7provided by MGI
    Official Full Name
    ribosomal protein L7provided by MGI
    Primary source
    MGI:MGI:98073
    See related
    Ensembl:ENSMUSG00000043716 AllianceGenome:MGI:98073
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rpl7a; Surf-3
    Summary
    A structural constituent of ribosome. Predicted to be involved in maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within translation. Located in cytoplasm and ribosome. Part of cytosolic large ribosomal subunit. Is active in synapse. Is expressed in several structures, including brain; early conceptus; female reproductive system; and liver. Orthologous to human RPL7 (ribosomal protein L7). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 611.3), liver E14 (RPKM 581.9) and 25 other tissues See more
    Orthologs
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    Genomic context

    See Rpl7 in Genome Data Viewer
    Location:
    1 A3; 1 4.94 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (16171519..16174657, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (16101295..16104433, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930444P10 gene Neighboring gene STARR-seq mESC enhancer starr_00336 Neighboring gene predicted gene 7634 Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:16094431-16094614 Neighboring gene retinol dehydrogenase 10 (all-trans) Neighboring gene CapStarr-seq enhancer MGSCv37_chr1:16167808-16168008 Neighboring gene staufen double-stranded RNA binding protein 2 Neighboring gene predicted gene 7568

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC102113

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 5S rRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables mRNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IC
    Inferred by Curator
    more info
    PubMed 
    enables structural constituent of ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in A band ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in postsynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in postsynaptic density ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in presynapse NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of ribonucleoprotein complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in ribosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in ribosome NAS
    Non-traceable Author Statement
    more info
    PubMed 
    is_active_in synapse EXP
    Inferred from Experiment
    more info
    PubMed 
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    large ribosomal subunit protein uL30
    Names
    60S ribosomal protein L7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_011291.5NP_035421.2  large ribosomal subunit protein uL30

      See identical proteins and their annotated locations for NP_035421.2

      Status: VALIDATED

      Source sequence(s)
      AK050656, BB839528, BY441493
      Consensus CDS
      CCDS14829.1
      UniProtKB/Swiss-Prot
      P14148, Q80UR0
      UniProtKB/TrEMBL
      Q3TK73, Q3UBI6, Q5M9N8
      Related
      ENSMUSP00000071616.7, ENSMUST00000058437.14
      Conserved Domains (1) summary
      TIGR01310
      Location:38270
      uL30_euk; 60S ribosomal protein uL30, eukaryotic form

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      16171519..16174657 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)